Literature DB >> 15313399

Modulation of poly(ADP-ribosylation) in apoptotic cells.

A Ivana Scovassi1, Marc Diederich.   

Abstract

Poly(ADP-ribosylation) is a post-translational modification of proteins playing a crucial role in DNA repair, replication, transcription and cell death. In this paper, the main features of this process have been reviewed, focusing on the best known poly(ADP-ribose) polymerizing enzyme, PARP-1, a DNA nick-sensor protein that uses beta-NAD+ to form polymers of ADP-ribose. The modulation of poly(ADP-ribosylation) during apoptosis and the possible effects of its inhibition on cell metabolism are discussed.

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Year:  2004        PMID: 15313399     DOI: 10.1016/j.bcp.2004.04.023

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN: 0006-2952            Impact factor:   5.858


  23 in total

Review 1.  The PARP family: insights into functional aspects of poly (ADP-ribose) polymerase-1 in cell growth and survival.

Authors:  T Jubin; A Kadam; M Jariwala; S Bhatt; S Sutariya; A R Gani; S Gautam; R Begum
Journal:  Cell Prolif       Date:  2016-06-22       Impact factor: 6.831

2.  Contribution of poly(ADP-ribose)polymerase-1 activation and apoptosis in trichloroethene-mediated autoimmunity.

Authors:  Gangduo Wang; Huaxian Ma; Jianling Wang; M Firoze Khan
Journal:  Toxicol Appl Pharmacol       Date:  2018-10-10       Impact factor: 4.219

3.  Apoptosis-like cell death induction and aberrant fibroblast properties in human incisional hernia fascia.

Authors:  Ramon Diaz; Maria T Quiles; Jordi Guillem-Marti; Manuel Lopez-Cano; Pere Huguet; Santiago Ramon-Y-Cajal; Jaume Reventos; Manel Armengol; Maria A Arbos
Journal:  Am J Pathol       Date:  2011-06       Impact factor: 4.307

4.  Crystal structure of inhibitor of growth 4 (ING4) dimerization domain reveals functional organization of ING family of chromatin-binding proteins.

Authors:  Simone Culurgioni; Inés G Muñoz; Alberto Moreno; Alicia Palacios; Maider Villate; Ignacio Palmero; Guillermo Montoya; Francisco J Blanco
Journal:  J Biol Chem       Date:  2012-02-09       Impact factor: 5.157

5.  RNA interference targeting mutant p53 inhibits growth and induces apoptosis in DU145 human prostate cancer cells.

Authors:  HaiBin Zhu; Qiqi Mao; Yiwei Lin; Kai Yang; Liping Xie
Journal:  Med Oncol       Date:  2010-09-21       Impact factor: 3.064

6.  Inhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130.

Authors:  Denise Campisi Hegan; Yuhong Lu; Gregory C Stachelek; Meredith E Crosby; Ranjit S Bindra; Peter M Glazer
Journal:  Proc Natl Acad Sci U S A       Date:  2010-01-19       Impact factor: 11.205

7.  Bruceine D induces apoptosis in human chronic myeloid leukemia K562 cells via mitochondrial pathway.

Authors:  Jian-Ye Zhang; Min-Ting Lin; Ho-Yi Tung; Si-Li Tang; Tao Yi; Ya-Zhou Zhang; Yi-Na Tang; Zhong-Zhen Zhao; Hu-Biao Chen
Journal:  Am J Cancer Res       Date:  2016-03-15       Impact factor: 6.166

8.  Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity.

Authors:  Verena Krähling; David A Stein; Martin Spiegel; Friedemann Weber; Elke Mühlberger
Journal:  J Virol       Date:  2008-12-24       Impact factor: 5.103

9.  Attenuated free cholesterol loading-induced apoptosis but preserved phospholipid composition of peritoneal macrophages from mice that do not express group VIA phospholipase A2.

Authors:  Shunzhong Bao; Yankun Li; Xiaoyong Lei; Mary Wohltmann; Wu Jin; Alan Bohrer; Clay F Semenkovich; Sasanka Ramanadham; Ira Tabas; John Turk
Journal:  J Biol Chem       Date:  2007-07-12       Impact factor: 5.157

10.  Poly(ADP-ribose) glycohydrolase silencing protects against H2O2-induced cell death.

Authors:  Christian Blenn; Felix R Althaus; Maria Malanga
Journal:  Biochem J       Date:  2006-06-15       Impact factor: 3.857

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