| Literature DB >> 15313246 |
Pascale Mathonet1, Jacques Fastrez.
Abstract
Rational design, usually guided by computational prediction, and selection from libraries of variants of natural proteins have been used with success in the engineering of novel non-natural receptors. Many of these engineered protein binders will find use in biotechnological, diagnostic and medical applications, sometimes in the place of natural antibodies.Mesh:
Substances:
Year: 2004 PMID: 15313246 DOI: 10.1016/j.sbi.2004.06.007
Source DB: PubMed Journal: Curr Opin Struct Biol ISSN: 0959-440X Impact factor: 6.809