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Literature DB >> 1531276

The effect of calcium and magnesium ions on urinary urokinase and sialidase activity.

C H van Aswegen¹, J C Dirksen van Sckalckwyk, P J du Toit, L Verster, R C Franz, D J du Plessis.

Abstract

The effect of a promoter (calcium) and an inhibitor (magnesium) of urolithiasis was spectrophotometrically studied on urokinase (0.45 IU) and sialidase (5 mM). Although these mineral did not affect the sialidase activity, total inhibition of urokinase activity was observed with either 0.05 M calcium chloride or 0.1 M magnesium chloride. This observation might explain why calcium and magnesium respectively function as a promoter and an inhibitor of stone formation.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1992 PMID： 1531276 DOI： 10.1007/bf00294333

Source DB: PubMed Journal: Urol Res ISSN： 0300-5623

17 in total

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Journal: Biochemistry Date: 1966-01 Impact factor: 3.162

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Authors: M Nikkilä; T Koivula; H Jokela
Journal: Eur Urol Date: 1989 Impact factor: 20.096

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Journal: Clin Sci (Lond) Date: 1982-01 Impact factor: 6.124

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Authors: C H van Aswegen; P Hurter; C A van der Merwe; D J du Plessis
Journal: Urol Res Date: 1989

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Authors: B Wiman; G Mellbring; M Rånby
Journal: Clin Chim Acta Date: 1983-01-24 Impact factor: 3.786

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Authors: C H van Aswegen; A W Neitz; P J Becker; D J du Plessis
Journal: Urol Res Date: 1988

7 in total

1. Meta-analysis of the urokinase gene 3'-UTR T/C polymorphism and susceptibility to urolithiasis.

Authors: Dawei Li; Jikai Liu; Juchao Ren; Lei Yan; Hainan Liu; Zhonghua Xu
Journal: Biomed Rep Date: 2013-03-07

2. Pyelonephritis: renal urokinase activity in rats on essential fatty acid diets.

Authors: P J du Toit; C H van Aswegen; J D Nel; B Strasheim; P J Becker; D J du Plessis
Journal: Urol Res Date: 1994

3. In vivo effects of urease-producing bacteria involved with the pathogenesis of infection-induced urolithiasis on renal urokinase and sialidase activity.

Authors: P J du Toit; C H van Aswegen; J A Nel; P L Steyn; A J Ligthelm; D J du Plessis
Journal: Urol Res Date: 1995

4. Effects of bacteria involved with the pathogenesis of infection-induced urolithiasis on the urokinase and sialidase (neuraminidase) activity.

Authors: P J du Toit; C H van Aswegen; P L Steyn; A Pols; D J du Plessis
Journal: Urol Res Date: 1992