Literature DB >> 15310517

Hyperarousal and insomnia.

M H Bonnet1, D L Arand.   

Abstract

Primary or psychophysiological insomnia has alternatively been viewed as either a predominantly psychological problem or as a predominantly physiological problem. Several early studies of patients were not able to document physiological differences, but more recent studies have found that many patients with primary insomnia take longer than control subjects to fall asleep on daytime nap tests despite feeling fatigued and they have elevated metabolic rate throughout both night and day. Other recent studies have found that increasing physiological arousal level for a week in normal sleepers produced the major secondary symptoms reported by insomniacs. In contrast, producing the disturbed sleep of insomniacs in a group of normal sleepers did not produce the typical pattern of secondary symptoms. Taken together, evidence is presented which supports the contention that primary insomniacs suffer from a disorder of hyperarousal and that the elevated arousal produces the poor sleep and other symptoms reported by patients. It is therefore suggested that new treatment strategies directed at reduction of arousal level be considered in these patients.

Entities:  

Year:  1997        PMID: 15310517     DOI: 10.1016/s1087-0792(97)90012-5

Source DB:  PubMed          Journal:  Sleep Med Rev        ISSN: 1087-0792            Impact factor:   11.609


  81 in total

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5.  Structural Brain Modifications in Primary Insomnia: Myth or Reality?

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6.  Insomnia with Short Sleep Duration: Nosological, Diagnostic, and Treatment Implications.

Authors:  Alexandros N Vgontzas; Julio Fernandez-Mendoza
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7.  I Keep a Close Watch on This Heart of Mine: Increased Interoception in Insomnia.

Authors:  Yishul Wei; Jennifer R Ramautar; Michele A Colombo; Diederick Stoffers; Germán Gómez-Herrero; Wisse P van der Meijden; Bart H W Te Lindert; Ysbrand D van der Werf; Eus J W Van Someren
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8.  Increased use-dependent plasticity in chronic insomnia.

Authors:  Rachel E Salas; Joseph M Galea; Alyssa A Gamaldo; Charlene E Gamaldo; Richard P Allen; Michael T Smith; Gabriela Cantarero; Barbara D Lam; Pablo A Celnik
Journal:  Sleep       Date:  2014-03-01       Impact factor: 5.849

9.  Wake High-Density Electroencephalographic Spatiospectral Signatures of Insomnia.

Authors:  Michele A Colombo; Jennifer R Ramautar; Yishul Wei; Germán Gomez-Herrero; Diederick Stoffers; Rick Wassing; Jeroen S Benjamins; Enzo Tagliazucchi; Ysbrand D van der Werf; Christian Cajochen; Eus J W Van Someren
Journal:  Sleep       Date:  2016-05-01       Impact factor: 5.849

10.  Neural circuitry of stress-induced insomnia in rats.

Authors:  Georgina Cano; Takatoshi Mochizuki; Clifford B Saper
Journal:  J Neurosci       Date:  2008-10-01       Impact factor: 6.167

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