Literature DB >> 15309739

Endoscopic identification of Peyer's patches of the terminal ileum in a patient with Crohn's disease.

Hiroshi Ishimoto1, Hajime Isomoto, Saburo Shikuwa, Chun-Yang Wen, Takashi Suematu, Masahiro Ito, Ikuo Murata, Hiromi Ishibashi, Shigeru Kohno.   

Abstract

We presented a 20-year-old patient with Crohn's disease (CD). Colonoscopy revealed longitudinal ulceration in the terminal ileum and rectal aphtoid ulcers. After treatment with mesalamine and total parenteral nutrition, repeat colonoscopy revealed a granular elevated area in the terminal ileum, which appeared as an irregular dome-like elevation with irregularly arranged villi on magnifying endoscopy. Biopsy specimens taken from the region showed microgranulomas and lymphoid hyperplasia. Scanning electron microscopy revealed the presence of M cells, confirming that the area corresponded to Peyer's patches. Peyer's patches by magnifying endoscopy and electron microscopy may provide insights into the pathogenesis of CD.

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Year:  2004        PMID： 15309739      PMCID： PMC4572213          DOI： 10.3748/wjg.v10.i18.2767

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN： 1007-9327            Impact factor:   5.742


  6 in total

1.  Distribution of Peyer's patches in the distal ileum.

Authors:  Herbert J Van Kruiningen; A Brian West; Benjamin J Freda; Kimberly A Holmes
Journal:  Inflamm Bowel Dis       Date:  2002-05       Impact factor: 5.325

2.  Crohn's disease (regional enteritis) of the large intestine and its distinction from ulcerative colitis.

Authors:  H E LOCKHART-MUMMERY; B C MORSON
Journal:  Gut       Date:  1960-06       Impact factor: 23.059

3.  Microbiology of the intestinal lymph follicle: a clue to elucidate causative microbial agent(s) in Crohn's disease.

Authors:  M Chiba; M Komatsu; M Iizuka; O Masamune; S Hoshina; M Kono
Journal:  Med Hypotheses       Date:  1998-11       Impact factor: 1.538

4.  The role of Peyer's patches in the age-related incidence of Crohn's disease.

Authors:  H J Van Kruiningen; L M Ganley; B J Freda
Journal:  J Clin Gastroenterol       Date:  1997-09       Impact factor: 3.062

5.  The significance of colonic mucosal lymphoid hyperplasia and aphthoid ulcers in Crohn's disease.

Authors:  K Hizawa; M Iida; K Aoyagi; M Fujishima
Journal:  Clin Radiol       Date:  1996-10       Impact factor: 2.350

6.  Pathogenesis of aphthoid ulcers in Crohn's disease: correlative findings by magnifying colonoscopy, electron microscopy, and immunohistochemistry.

Authors:  Y Fujimura; R Kamoi; M Iida
Journal:  Gut       Date:  1996-05       Impact factor: 23.059
  6 in total
  4 in total

1.  Magnifying videoendoscopic findings of Peyer's patches in the terminal ileum of Crohn's disease.

Authors:  Saburo Shikuwa; Hajime Isomoto; Yohei Mizuta; Takashi Suematsu; Masahiro Ito; Shigeru Kohno
Journal:  Gut       Date:  2007-06       Impact factor: 23.059

2.  The role of bacteria in the pathogenesis of inflammatory bowel disease.

Authors:  Melissa Friswell; Barry Campbell; Jonathan Rhodes
Journal:  Gut Liver       Date:  2010-09-24       Impact factor: 4.519

3.  Peyer's Patches in the Terminal Ileum in Ulcerative Colitis: Magnifying Endoscopic Findings.

Authors:  Hiroyuki Ishii; Hajime Isomoto; Saburo Shikuwa; Tomayoshi Hayashi; Naoki Inoue; Naoyuki Yamaguchi; Ken Ohnita; Atsushi Nanashima; Masahiro Ito; Kazuhiko Nakao; Shigeru Kohno
Journal:  J Clin Biochem Nutr       Date:  2010-02-27       Impact factor: 3.114

Review 4.  Physicochemical factors that affect metal and metal oxide nanoparticle passage across epithelial barriers.

Authors:  Alison Elder; Sadasivan Vidyasagar; Lisa DeLouise
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2009 Jul-Aug
  4 in total

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