Literature DB >> 15309139

Prehospital Treatment of Status Epilepticus with Benzodiazepines Is Effective and Safe.

Jaideep Kapur1.   

Abstract

Benzodiazepines are an effective and safe treatment of status epilepticus and serial seizures when used in an out-of-hospital setting. Intravenously administered lorazepam is somewhat superior to diazepam for the treatment of status epilepticus. Treatment of status epilepticus should be initiated when seizures have lasted 5-7 minutes.

Entities:  

Year:  2002        PMID： 15309139      PMCID： PMC321036          DOI： 10.1111/j.1535-7597.2002.00045.x

Source DB:  PubMed          Journal:  Epilepsy Curr        ISSN： 1535-7511            Impact factor:   7.872


  23 in total

1.  How long do new-onset seizures in children last?

Authors:  S Shinnar; A T Berg; S L Moshe; R Shinnar
Journal:  Ann Neurol       Date:  2001-05       Impact factor: 10.422

2.  Rectal diazepam gel for treatment of acute repetitive seizures. The North American Diastat Study Group.

Authors:  R L Kriel; J C Cloyd; J M Pellock; W G Mitchell; J J Cereghino; N P Rosman
Journal:  Pediatr Neurol       Date:  1999-04       Impact factor: 3.372

3.  Status epilepticus-induced neuronal loss in humans without systemic complications or epilepsy.

Authors:  D G Fujikawa; H H Itabashi; A Wu; S S Shinmei
Journal:  Epilepsia       Date:  2000-08       Impact factor: 5.864

4.  The prehospital treatment of status epilepticus (PHTSE) study: design and methodology.

Authors:  D H Lowenstein; B K Alldredge; F Allen; J Neuhaus; M Corry; M Gottwald; N O'Neil; S Ulrich; S M Isaacs; A Gelb
Journal:  Control Clin Trials       Date:  2001-06

Review 5.  The biochemical basis and pathophysiology of status epilepticus.

Authors:  E Lothman
Journal:  Neurology       Date:  1990-05       Impact factor: 9.910

Review 6.  Systemic effects of generalized convulsive status epilepticus.

Authors:  N Y Walton
Journal:  Epilepsia       Date:  1993       Impact factor: 5.864

7.  Double-blind study of lorazepam and diazepam in status epilepticus.

Authors:  I E Leppik; A T Derivan; R W Homan; J Walker; R E Ramsay; B Patrick
Journal:  JAMA       Date:  1983-03-18       Impact factor: 56.272

8.  A comparison of rectal diazepam gel and placebo for acute repetitive seizures.

Authors:  F E Dreifuss; N P Rosman; J C Cloyd; J M Pellock; R I Kuzniecky; W D Lo; F Matsuo; G B Sharp; J A Conry; D C Bergen; W E Bell
Journal:  N Engl J Med       Date:  1998-06-25       Impact factor: 91.245

9.  Benzodiazepine concentrations in brain directly reflect receptor occupancy: studies of diazepam, lorazepam, and oxazepam.

Authors:  D J Greenblatt; V H Sethy
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530

10.  Determinants of mortality in status epilepticus.

Authors:  A R Towne; J M Pellock; D Ko; R J DeLorenzo
Journal:  Epilepsia       Date:  1994 Jan-Feb       Impact factor: 5.864
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  6 in total

1.  Treatment of pediatric status epilepticus.

Authors:  Tobias Loddenkemper; Howard P Goodkin
Journal:  Curr Treat Options Neurol       Date:  2011-12       Impact factor: 3.598

2.  Pharmacokinetics of diazepam administered intramuscularly by autoinjector versus rectal gel in healthy subjects: a phase I, randomized, open-label, single-dose, crossover, single-centre study.

Authors:  Michael J Lamson; Diane Sitki-Green; Gerald L Wannarka; Michael Mesa; Paul Andrews; John Pellock
Journal:  Clin Drug Investig       Date:  2011       Impact factor: 2.859

3.  Guidelines for the evaluation and management of status epilepticus.

Authors:  Gretchen M Brophy; Rodney Bell; Jan Claassen; Brian Alldredge; Thomas P Bleck; Tracy Glauser; Suzette M Laroche; James J Riviello; Lori Shutter; Michael R Sperling; David M Treiman; Paul M Vespa
Journal:  Neurocrit Care       Date:  2012-08       Impact factor: 3.210

4.  Status epilepticus increases the intracellular accumulation of GABAA receptors.

Authors:  Howard P Goodkin; Jwu-Lai Yeh; Jaideep Kapur
Journal:  J Neurosci       Date:  2005-06-08       Impact factor: 6.167

5.  Responsiveness of Status Epilepticus to Treatment with Diazepan Decreases Rapidly as Seizure Duration Increases.

Authors:  Howard P. Goodkin; Jaideep Kapur
Journal:  Epilepsy Curr       Date:  2003-01       Impact factor: 7.872

6.  First-line medication dosing in pediatric refractory status epilepticus.

Authors:  Alejandra Vasquez; Marina Gaínza-Lein; Nicholas S Abend; Marta Amengual-Gual; Anne Anderson; Ravindra Arya; J Nicholas Brenton; Jessica L Carpenter; Kevin Chapman; Justice Clark; Raquel Farias-Moeller; William D Gaillard; Tracy Glauser; Joshua L Goldstein; Howard P Goodkin; Rejean M Guerriero; Kush Kapur; Yi-Chen Lai; Tiffani L McDonough; Mohamad A Mikati; Lindsey A Morgan; Edward J Novotny; Adam P Ostendorf; Eric T Payne; Katrina Peariso; Juan Piantino; James J Riviello; Kumar Sannagowdara; Robert C Tasker; Dmitry Tchapyjnikov; Alexis Topjian; Mark S Wainwright; Angus Wilfong; Korwyn Williams; Tobias Loddenkemper
Journal:  Neurology       Date:  2020-09-10       Impact factor: 9.910
  6 in total

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