Literature DB >> 15308543

SNP Chart: an integrated platform for visualization and interpretation of microarray genotyping data.

Scott J Tebbutt1, Igor V Opushnyev, Ben W Tripp, Ayaz M Kassamali, Wendy L Alexander, Marilyn I Andersen.   

Abstract

UNLABELLED: SNP Chart is a Java application for the visualization and interpretation of microarray genotyping data primarily derived from arrayed primer extension-based chemistries. Spot intensity output files from microarray analysis tools are imported into SNP Chart, together with a multi-channel TIFF image of the original array experiment and a list of the actual single nucleotide polymorphisms (SNPs) being tested. Data from different and/or replicate probes that interrogate the same SNP, but that are scattered across the array grid, can be reassembled into a single chart format, specific for the SNP. This allows a quick and very effective 'visualization'/'quality control' of the data from multiple probes for the same SNP that can be easily interpreted and manually scored as a genotype. AVAILABILITY: http://www.snpchart.ca.

Mesh:

Year:  2004        PMID: 15308543     DOI: 10.1093/bioinformatics/bth470

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  3 in total

1.  Bayesian Gaussian Mixture Models for High-Density Genotyping Arrays.

Authors:  Chiara Sabatti; Kenneth Lange
Journal:  J Am Stat Assoc       Date:  2008-03-01       Impact factor: 5.033

2.  Dynamic variable selection in SNP genotype autocalling from APEX microarray data.

Authors:  Mohua Podder; William J Welch; Ruben H Zamar; Scott J Tebbutt
Journal:  BMC Bioinformatics       Date:  2006-11-30       Impact factor: 3.169

3.  Robust SNP genotyping by multiplex PCR and arrayed primer extension.

Authors:  Mohua Podder; Jian Ruan; Ben W Tripp; Zane E Chu; Scott J Tebbutt
Journal:  BMC Med Genomics       Date:  2008-01-31       Impact factor: 3.063

  3 in total

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