| Literature DB >> 15308199 |
S J González1, M R Bonomi, G A Santa Cruz, H R Blaumann, O A Calzetta Larrieu, P Menéndez, R Jiménez Rebagliati, J Longhino, D B Feld, M A Dagrosa, C Argerich, S G Castiglia, D A Batistoni, S J Liberman, B M C Roth.
Abstract
A Phase I/II protocol for treating cutaneuos melanomas with BNCT was designed in Argentina by the Comisión Nacional de Energía Atómica and the medical center Instituto Roffo. The first of a cohort of thirty planned patients was treated on October 9, 2003. This article depicts the protocol-based procedure and describes the first clinical case, treatment regime and planning, patient irradiation, retrospective dosimetric analysis and clinical outcome. Considering the low acute skin toxicity and the complete response in 21 of the 25 subcutaneous melanoma nodules treated, a second irradiation was performed in a different location of the extremity of the same patient. The corresponding clinical outcome is still under evaluation.Entities:
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Year: 2004 PMID： 15308199 DOI： 10.1016/j.apradiso.2004.05.060
Source DB: PubMed Journal: Appl Radiat Isot ISSN： 0969-8043 Impact factor: 1.513