Literature DB >> 1530636

Photosensitized formation of 8-hydroxydeoxyguanosine in cellular DNA by riboflavin.

F Yamamoto1, S Nishimura, H Kasai.   

Abstract

Photosensitized formation of 8-hydroxydeoxyguanosine (oh8dG) in DNA by riboflavin has recently been shown in vitro. The present study describes the formation of oh8dG in cellular DNA by photo-irradiation of cultured mammalian cells in the presence of riboflavin. Formation of oh8dG was dependent on the concentration of riboflavin as well as the duration of photoirradiation. These results suggest that photosensitized formation of oh8dG in DNA by riboflavin may be involved in photocarcinogenesis.

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Year:  1992        PMID： 1530636     DOI： 10.1016/0006-291x(92)91268-u

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  8 in total

1.  UVA irradiation of riboflavin generates oxygen-dependent hydroxyl radicals.

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2.  Antimutator role of the DNA glycosylase mutY gene in Helicobacter pylori.

Authors:  Shuyan Huang; Josephine Kang; Martin J Blaser
Journal:  J Bacteriol       Date:  2006-09       Impact factor: 3.490

3.  Lack of p53 mutations and loss of heterozygosity in non-cultured human melanocytic lesions.

Authors:  T Papp; M Jafari; D Schiffmann
Journal:  J Cancer Res Clin Oncol       Date:  1996       Impact factor: 4.553

4.  Small molecule alteration of RNA sequence in cells and animals.

Authors:  Lirui Guan; Yiling Luo; William W Ja; Matthew D Disney
Journal:  Bioorg Med Chem Lett       Date:  2017-10-18       Impact factor: 2.823

5.  Analysis of ras mutations in human melanocytic lesions: activation of the ras gene seems to be associated with the nodular type of human malignant melanoma.

Authors:  M Jafari; T Papp; S Kirchner; U Diener; D Henschler; G Burg; D Schiffmann
Journal:  J Cancer Res Clin Oncol       Date:  1995       Impact factor: 4.553

6.  Lack of direct involvement of 8-hydroxy-2'-deoxyguanosine in hypoxanthine-guanine phosphoribosyltransferase mutagenesis in V79 cells treated with N,N'-bis(2-hydroxyperoxy-2-methoxyethyl)-1,4,5,8-naphthalenetetracarboxylic-diimide (NP-III) or riboflavin.

Authors:  Madoka Nakajima; Toru Takeuchi; Keiki Ogino; Kanehisa Morimoto
Journal:  Jpn J Cancer Res       Date:  2002-03

Review 7.  Atypical BRAF and NRAS Mutations in Mucosal Melanoma.

Authors:  Nicolas Dumaz; Fanélie Jouenne; Julie Delyon; Samia Mourah; Armand Bensussan; Céleste Lebbé
Journal:  Cancers (Basel)       Date:  2019-08-08       Impact factor: 6.639

Review 8.  Spatiotemporal dynamics of DNA repair proteins following laser microbeam induced DNA damage - when is a DSB not a DSB?

Authors:  Pamela Reynolds; Stanley W Botchway; Anthony W Parker; Peter O'Neill
Journal:  Mutat Res       Date:  2013-05-17       Impact factor: 2.433
  8 in total

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