Literature DB >> 15305319

In vitro leishmanicidal activity of some scarce natural products.

Marii Takahashi1, Hiroyuki Fuchino, Setsuko Sekita, Motoyoshi Satake.   

Abstract

Leishmanicidal activity of 46 natural products including several fern and Betula constituents was examined. Several pterosin and atisene compounds from ferns had high activity. Among the triterpenoids the carboxyl group was found to be important for activity. In the diarylheptanoids, the linear-type and the diphenylether-type showed significant activity, and it was found that the carbonyl group at C-11 is necessary for the activity of biphenyl-types.

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Year:  2004        PMID： 15305319     DOI： 10.1002/ptr.1502

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  8 in total

1.  Herbal extract targets in Leishmania tropica.

Authors:  Bassim I Mohammad; Maani N Al Shammary; Roaa H Abdul Mageed; Nasser Ghaly Yousif
Journal:  J Parasit Dis       Date:  2014-02-16

2.  Leishmanicidal activity of saponins isolated from the leaves of Eclipta prostrata and Gymnema sylvestre.

Authors:  Venkatesan Gopiesh Khanna; Krishnan Kannabiran; Giulia Getti
Journal:  Indian J Pharmacol       Date:  2009-02       Impact factor: 1.200

3.  Thymol and eugenol derivatives as potential antileishmanial agents.

Authors:  Selene Maia de Morais; Nadja Soares Vila-Nova; Claudia Maria Leal Bevilaqua; Fernanda Cristina Rondon; Carlos Henrique Lobo; Arlindo de Alencar Araripe Noronha Moura; Antônia Débora Sales; Ana Paula Ribeiro Rodrigues; José Ricardo de Figuereido; Claudio Cabral Campello; Mary E Wilson; Heitor Franco de Andrade
Journal:  Bioorg Med Chem       Date:  2014-09-06       Impact factor: 3.641

4.  Diarylheptanoid analogues from the rhizomes of Zingiber officinale and their anti-tumour activity.

Authors:  Ting Li; Da-Bo Pan; Qian-Qian Pang; Mi Zhou; Xiao-Jun Yao; Xin-Sheng Yao; Hai-Bo Li; Yang Yu
Journal:  RSC Adv       Date:  2021-09-02       Impact factor: 4.036

Review 5.  Chemical Strategies towards the Synthesis of Betulinic Acid and Its More Potent Antiprotozoal Analogues.

Authors:  André Barreto Cunha; Ronan Batista; María Ángeles Castro; Jorge Mauricio David
Journal:  Molecules       Date:  2021-02-18       Impact factor: 4.411

6.  Leishmanicidal Activity of Betulin Derivatives in Leishmania amazonensis; Effect on Plasma and Mitochondrial Membrane Potential, and Macrophage Nitric Oxide and Superoxide Production.

Authors:  Wilmer Alcazar; Sami Alakurtti; Maritza Padrón-Nieves; Maija Liisa Tuononen; Noris Rodríguez; Jari Yli-Kauhaluoma; Alicia Ponte-Sucre
Journal:  Microorganisms       Date:  2021-02-04

Review 7.  Potential of Triterpenic Natural Compound Betulinic Acid for Neglected Tropical Diseases New Treatments.

Authors:  Vinícius Rocha; Helenita Quadros; Cássio Meira; Laís Silva; Dahara Carvalho; Katharine Hodel; Diogo Moreira; Milena Soares
Journal:  Biomedicines       Date:  2022-04-01

8.  Antidiabetic effects of pterosin A, a small-molecular-weight natural product, on diabetic mouse models.

Authors:  Feng-Lin Hsu; Chun-Fa Huang; Ya-Wen Chen; Yuan-Peng Yen; Cheng-Tien Wu; Biing-Jiun Uang; Rong-Sen Yang; Shing-Hwa Liu
Journal:  Diabetes       Date:  2012-10-15       Impact factor: 9.461
  8 in total

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