Literature DB >> 15305098

Thoracoamniotic shunts: fetal treatment of pleural effusions and congenital cystic adenomatoid malformations.

R Douglas Wilson1, Jason K Baxter, Mark P Johnson, Mary King, Stefanie Kasperski, Timothy M Crombleholme, Alan W Flake, Holly L Hedrick, Lori J Howell, N Scott Adzick.   

Abstract

OBJECTIVE: To determine whether fetuses that underwent thoracoamniotic shunt placement for treatment of pleural effusion (PE) or macrocystic congenital cystic adenomatoid malformation (CCAM) have an improved outcome as compared with an untreated population.
METHODS: A retrospective review from a single tertiary center was performed using thoracoamniotic shunt placement to treat PE or macrocystic CCAM between 1998 and 2001. Thoracoamniotic shunts were used on 26 occasions in 19 pregnancies.
RESULTS: The average gestational age at the diagnosis of PE and CCAM was 22 + 4 and 20 + 0 weeks, respectively. Shunts were offered in pregnancies complicated by hydrops or at significant risk for pulmonary hypoplasia. Shunts were placed at 26 + 2 weeks (average) and 23 + 1 weeks (average) in the PE and CCAM groups, respectively. In CCAM patients, the mean pre- and postshunting mass volumes were 50.5 and 25.7 cm(3), representing a 51% reduction in mass volume following shunt placement. In the PE group, the average delivery age was 33 + 5 weeks, with an average shunt placement to delivery time of 7 + 3 weeks. In the CCAM group, the average delivery was 33 + 3 weeks, with an average shunt placement to delivery time of 10 + 2 weeks. The postnatal survival rates were 67% (6/9) and 70% (7/10) in the PE and CCAM groups, respectively.
CONCLUSIONS: (1) Thoracoamniotic shunts should be considered as a treatment option for selected PE or macrocystic CCAM fetuses with hydrops or a significant risk for pulmonary hypoplasia; (2) the neonatal survival with shunting was similar for PE and CCAM groups and was improved as compared with literature reports, and (3) fetuses with CCAM presented earlier with hydrops than those with PE. Successful shunting resulted in a prolongation of pregnancy into the 3rd trimester in both groups. Copyright 2004 S. Karger AG, Basel

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Year:  2004        PMID: 15305098     DOI: 10.1159/000078994

Source DB:  PubMed          Journal:  Fetal Diagn Ther        ISSN: 1015-3837            Impact factor:   2.587


  8 in total

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Authors:  Muhammad Choudhry; David Drake
Journal:  Pediatr Surg Int       Date:  2015-01-04       Impact factor: 1.827

Review 2.  Biomaterials in fetal surgery.

Authors:  Sally M Winkler; Michael R Harrison; Phillip B Messersmith
Journal:  Biomater Sci       Date:  2019-05-17       Impact factor: 6.843

3.  Refractory tension pneumothorax as a result of an internally displaced thoracoamniotic shunt in an infant with a congenital pulmonary airway malformation.

Authors:  Brenda Hiu Yan Law; Ioana Bratu; Venu Jain; Marc-Antoine Landry
Journal:  BMJ Case Rep       Date:  2016-07-28

4.  Inadvertent chest tube insertion in congenital cystic adenomatoid malformation and congenital lobar emphysema-highlighting an important problem.

Authors:  Shailesh M Prabhu; Subhasis Roy Choudhury; Ravi S Solanki; Gurucharan S Shetty; Surenderkumar Agarwala
Journal:  Indian J Radiol Imaging       Date:  2013-01

Review 5.  Congenital cystic lung disease: contemporary antenatal and postnatal management.

Authors:  Richard G Azizkhan; Timothy M Crombleholme
Journal:  Pediatr Surg Int       Date:  2008-04-05       Impact factor: 1.827

6.  Percutaneous in utero thoracoamniotic shunt creation for fetal thoracic abnormalities leading to nonimmune hydrops.

Authors:  Sarah B White; Sean M Tutton; William S Rilling; Randall S Kuhlmann; Erika L Peterson; Thomas R Wigton; Mary B Ames
Journal:  J Vasc Interv Radiol       Date:  2014-04-01       Impact factor: 3.464

Review 7.  The fetal respiratory system as target for antenatal therapy.

Authors:  J Toelen; M Carlon; F Claus; R Gijsbers; I Sandaite; K Dierickx; R Devlieger; K Devriendt; A Debeer; M Proesmans; Z Debyser; A J Deprest
Journal:  Facts Views Vis Obgyn       Date:  2011

Review 8.  Successfully treated congenital cystic adenomatoid malformation by open fetal surgery: A care-compliant case report of a 5-year follow-up and review of the literature.

Authors:  Dazhi Fan; Shuzhen Wu; Rui Wang; Yi Huang; Yao Fu; Wen Ai; Meng Zeng; Xiaoling Guo; Zhengping Liu
Journal:  Medicine (Baltimore)       Date:  2017-01       Impact factor: 1.889

  8 in total

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