Literature DB >> 15304635

The pH of the secretory pathway: measurement, determinants, and regulation.

Paul Paroutis1, Nicolas Touret, Sergio Grinstein.   

Abstract

The luminal pH of the secretory pathway plays a critical role in the posttranslational modification and sorting of proteins and lipids. The pH of each one of the organelles that constitute the pathway is unique, becoming more acidic as the biosynthetic cargo approaches its destination. The methods used for measurement of pH in the secretory pathway, its determinants, and its regulation are the subjects of this review.

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Mesh：

Year:  2004        PMID： 15304635     DOI： 10.1152/physiol.00005.2004

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  159 in total

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