Literature DB >> 15304631

Hydroxylation of HIF-1: oxygen sensing at the molecular level.

Gregg L Semenza1.   

Abstract

The ability to sense and respond to changes in oxygenation represents a fundamental property of all metazoan cells. The discovery of the transcription factor HIF-1 has led to the identification of protein hydroxylation as a mechanism by which changes in PO2 are transduced to effect changes in gene expression.

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Year:  2004        PMID： 15304631     DOI： 10.1152/physiol.00001.2004

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  284 in total

1.  Prolyl 4-hydroxylase genes are subjected to alternative splicing in roots of maize seedlings under waterlogging.

Authors:  Xiling Zou; Yuanyuan Jiang; Yonglian Zheng; Meidong Zhang; Zuxin Zhang
Journal:  Ann Bot       Date:  2011-10-03       Impact factor: 4.357

Review 2.  Theoretical models for coronary vascular biomechanics: progress & challenges.

Authors:  Sarah L Waters; Jordi Alastruey; Daniel A Beard; Peter H M Bovendeerd; Peter F Davies; Girija Jayaraman; Oliver E Jensen; Jack Lee; Kim H Parker; Aleksander S Popel; Timothy W Secomb; Maria Siebes; Spencer J Sherwin; Rebecca J Shipley; Nicolas P Smith; Frans N van de Vosse
Journal:  Prog Biophys Mol Biol       Date:  2010-10-30       Impact factor: 3.667

3.  Prevention of radiation-induced bone pathology through combined pharmacologic cytoprotection and angiogenic stimulation.

Authors:  Alexis Donneys; Noah S Nelson; Joseph E Perosky; Yekaterina Polyatskaya; Jose J Rodriguez; Christian Figueredo; Cheyenne A Vasseli; Hannah C Ratliff; Sagar S Deshpande; Kenneth M Kozloff; Steven R Buchman
Journal:  Bone       Date:  2015-12-23       Impact factor: 4.398

4.  Time-dependent PPARγ Modulation of HIF-1α Signaling in Hypoxic Pulmonary Artery Smooth Muscle Cells.

Authors:  Justine I Blum; Kaiser M Bijli; Tamara C Murphy; Jennifer M Kleinhenz; C Michael Hart
Journal:  Am J Med Sci       Date:  2016-04-04       Impact factor: 2.378

Review 5.  Proteostasis and REDOX state in the heart.

Authors:  Elisabeth S Christians; Ivor J Benjamin
Journal:  Am J Physiol Heart Circ Physiol       Date:  2011-10-14       Impact factor: 4.733

Review 6.  Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to Hypoxia.

Authors:  Muhammad Zaeem Noman; Meriem Hasmim; Yosra Messai; Stéphane Terry; Claudine Kieda; Bassam Janji; Salem Chouaib
Journal:  Am J Physiol Cell Physiol       Date:  2015-08-26       Impact factor: 4.249

7.  Hypoxia-Inducible Factor α and Hif-prolyl Hydroxylase Characterization and Gene Expression in Short-Time Air-Exposed Mytilus galloprovincialis.

Authors:  Alessia Giannetto; Maria Maisano; Tiziana Cappello; Sabrina Oliva; Vincenzo Parrino; Antonino Natalotto; Giuseppe De Marco; Chiara Barberi; Orazio Romeo; Angela Mauceri; Salvatore Fasulo
Journal:  Mar Biotechnol (NY)       Date:  2015-08-16       Impact factor: 3.619

8.  A novel erythrocytosis-associated PHD2 mutation suggests the location of a HIF binding groove.

Authors:  Melanie J Percy; Paul W Furlow; Philip A Beer; Terence R J Lappin; Mary Frances McMullin; Frank S Lee
Journal:  Blood       Date:  2007-06-19       Impact factor: 22.113

Review 9.  Immediate and long-term responses of the carotid body to high altitude.

Authors:  David F Wilson; Arijit Roy; Sukhamay Lahiri
Journal:  High Alt Med Biol       Date:  2005       Impact factor: 1.981

10.  Hypoxia-inducible factor 1alpha (HIF1A) mediates distinct steps of rat trophoblast differentiation in gradient oxygen.

Authors:  Amy D Gultice; Kashmira Kulkarni-Datar; Thomas L Brown
Journal:  Biol Reprod       Date:  2008-09-24       Impact factor: 4.285
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