Literature DB >> 15303451

Type 2 diabetes mellitus in the pediatric population.

Allyson S Gaylor1, Michelle E Condren.   

Abstract

Type 2 diabetes mellitus, once considered a disease only of adults, is now being diagnosed at an increasingly alarming rate in children. It is still unclear whether the presentation, risk factors, course, and treatment of the disease are the same in children as they are in adults. Pediatric-specific prevalence is being linked to obesity and inactivity, and risk factors include being overweight, family history of the disease, and conditions of insulin resistance such as puberty. Although the clinical presentations of types 1 and 2 diabetes often are different, they can be similar, which makes it difficult to differentiate between the two. Metformin is the only drug approved for the treatment of type 2 diabetes in children, but other drugs are being studied. Prevention is essential. It is critical that health care professionals and the public are educated about this disease and that studies are conducted that focus on children with type 2 diabetes.

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Year:  2004        PMID: 15303451     DOI: 10.1592/phco.24.9.871.36099

Source DB:  PubMed          Journal:  Pharmacotherapy        ISSN: 0277-0008            Impact factor:   4.705


  5 in total

Review 1.  Drug-induced acid-base disorders.

Authors:  Daniel Kitterer; Matthias Schwab; M Dominik Alscher; Niko Braun; Joerg Latus
Journal:  Pediatr Nephrol       Date:  2014-11-05       Impact factor: 3.714

Review 2.  Clinical Pharmacokinetics and Pharmacodynamics of Antihyperglycemic Medications in Children and Adolescents with Type 2 Diabetes Mellitus.

Authors:  Fatemeh Akhlaghi; Kelly L Matson; Amir Hooshang Mohammadpour; Meghan Kelly; Asieh Karimani
Journal:  Clin Pharmacokinet       Date:  2017-06       Impact factor: 6.447

3.  Survey of childhood diabetes and impact of school level educational interventions in rural schools in Karimnagar district.

Authors:  A Avasarala Kameswararao; Anilkrishna Bachu
Journal:  Int J Diabetes Dev Ctries       Date:  2009-04

4.  Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma.

Authors:  Ambrish Kumar; Nadia Al-Sammarraie; Donald J DiPette; Ugra S Singh
Journal:  Oncotarget       Date:  2014-11-30

Review 5.  Type 2 diabetes mellitus in children and adolescents: a relatively new clinical problem within pediatric practice.

Authors:  O R Temneanu; L M Trandafir; M R Purcarea
Journal:  J Med Life       Date:  2016 Jul-Sep
  5 in total

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