Literature DB >> 15303400

An improved method for emergent decontamination of ocular and dermal hydrofluoric acid splashes.

Kjell Soderberg1, Petri Kuusinen, Laurence Mathieu, Alan H Hall.   

Abstract

Accidental hydrofluoric acid (HF) splashes often occur in industrial settings. HF easily penetrates into tissues by initial acid action allowing fluoride ions to penetrate deeply, chelating calcium and magnesium. Resultant hypocalcemia and hypomagnesemia can be fatal. This report describes the utilization of Hexafluorine--a hypertonic, amphoteric, chelating decontamination solution--in workplaces where water decontamination followed by calcium gluconate inunction failed to prevent HF burns and systemic toxicity. Between 1998 and 1999, 16 cases of ocular and dermal HF splashes with either 70% HF or 6% HF/15% nitric acid (HNO3) were decontaminated with Hexafluorine at the worksite. HF burns did not develop and medical treatment other than initial decontamination was not reQuired in 12/16 (75%). In 7/16 (44%) cases, lost work time corresponded to duration of hospital observation (mean < 1 d).

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Year:  2004        PMID: 15303400

Source DB:  PubMed          Journal:  Vet Hum Toxicol        ISSN: 0145-6296


  4 in total

1.  Treatment of hydrofluoric acid exposure to the eye.

Authors:  Katherine Atley; Edward Ridyard
Journal:  Int J Ophthalmol       Date:  2015-02-18       Impact factor: 1.779

2.  Part 2. Comparison of emergency washing solutions in 70% hydrofluoric acid-burned human skin in an established ex vivo explants model.

Authors:  François Burgher; Laurence Mathieu; Elian Lati; Philippe Gasser; Laurent Peno-Mazzarino; Joël Blomet; Alan H Hall; Howard I Maibach
Journal:  Cutan Ocul Toxicol       Date:  2010-11-18       Impact factor: 1.820

3.  Hydrofluoric acid burns in the western Zhejiang Province of China: a 10-year epidemiological study.

Authors:  Yuanhai Zhang; Jianfen Zhang; Xinhua Jiang; Liangfang Ni; Chunjiang Ye; Chunmao Han; Komal Sharma; Xingang Wang
Journal:  J Occup Med Toxicol       Date:  2016-12-07       Impact factor: 2.646

Review 4.  Hydrofluoric Acid: Burns and Systemic Toxicity, Protective Measures, Immediate and Hospital Medical Treatment.

Authors:  Emilija Bajraktarova-Valjakova; Vesna Korunoska-Stevkovska; Silvana Georgieva; Kiro Ivanovski; Cvetanka Bajraktarova-Misevska; Aneta Mijoska; Anita Grozdanov
Journal:  Open Access Maced J Med Sci       Date:  2018-11-20
  4 in total

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