Literature DB >> 15302528

Structure and function of snake venom cysteine-rich secretory proteins.

Yasuo Yamazaki1, Takashi Morita.   

Abstract

Cysteine-rich secretory proteins (CRISPs) are primarily found in the epididymis of mammals and are expressed in diverse organisms. However, the functions of most CRISPs remain unknown. Recent studies reveal that CRISPs are widely distributed in snake venoms and that they inhibit smooth muscle contraction and cyclic nucleotide-gated ion channels. In this review, we discuss recent findings on several snake venom-derived CRISPs.

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Year:  2004        PMID： 15302528     DOI： 10.1016/j.toxicon.2004.05.023

Source DB:  PubMed          Journal:  Toxicon        ISSN： 0041-0101            Impact factor:   3.033


  85 in total

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