Literature DB >> 15302523

About the toxicity of some Strychnos species and their alkaloids.

Geneviève Philippe1, Luc Angenot, Monique Tits, Michel Frédérich.   

Abstract

Poisons are widespread in plants and animals and humankind has often tried to turn them to its own advantage. Owing to their poisonous properties, some species of Strychnos genus have been employed mainly in hunting and fishing, as an adjunct to weapons used not only in the search of food and clothes, but also for preventing depredation by wild animals. They have been employed for martial and criminal purposes and also as a means of determining guilt or innocence. By their nature, poisons such as strychnine and curare affect the functioning of the victim's body; this also means that they have been, and are, an important source of pharmacological tools and medicines all over the world. With such potentially dangerous substances, care in medication is essential to avoid complications by overdose. All these points are approached in the present review.

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Year:  2004        PMID: 15302523     DOI: 10.1016/j.toxicon.2004.05.006

Source DB:  PubMed          Journal:  Toxicon        ISSN: 0041-0101            Impact factor:   3.033


  25 in total

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Authors:  Chenzhi Hou; Ruowen Zhang; Kexia Zhang; Xiaohui Chen
Journal:  Metab Brain Dis       Date:  2017-08-29       Impact factor: 3.584

2.  Phytochemical study, cytotoxic, analgesic, antipyretic and anti-inflammatory activities of Strychnos nux-vomica.

Authors:  Omayma A Eldahshan; Mohamed M Abdel-Daim
Journal:  Cytotechnology       Date:  2014-04-08       Impact factor: 2.058

3.  Neuro-pharmacological evaluation of anticonvulsant and neuroprotective activity of Cocculus laurifolius leaves in wistar rats.

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Journal:  Metab Brain Dis       Date:  2019-04-16       Impact factor: 3.584

4.  Investigation of the protective effect of Paeonia lactiflora on Semen Strychni-induced neurotoxicity based on monitoring nine potential neurotoxicity biomarkers in rat serum and brain tissue.

Authors:  Huiyan Shi; Chenzhi Hou; Liqiang Gu; Hang Xing; Meiyu Zhang; Longshan Zhao; Kaishun Bi; Xiaohui Chen
Journal:  Metab Brain Dis       Date:  2016-08-13       Impact factor: 3.584

5.  Efficacy of Strychnos spinosa (Lam.) and Solanum incanum L. aqueous fruit extracts against cattle ticks.

Authors:  James Madzimure; Emmanuel T Nyahangare; Humphrey Hamudikuwanda; Thokozani Hove; Steve R Belmain; Philip C Stevenson; Brighton M Mvumi
Journal:  Trop Anim Health Prod       Date:  2013-02-28       Impact factor: 1.559

6.  Antileishmanial activity and evaluation of the mechanism of action of strychnobiflavone flavonoid isolated from Strychnos pseudoquina against Leishmania infantum.

Authors:  Paula S Lage; Miguel A Chávez-Fumagalli; Juliana T Mesquita; Laís M Mata; Simone O A Fernandes; Valbert N Cardoso; Manuel Soto; Carlos A P Tavares; João P V Leite; Andre G Tempone; Eduardo A F Coelho
Journal:  Parasitol Res       Date:  2015-09-07       Impact factor: 2.289

7.  Phylogenomics of ligand-gated ion channels predicts monepantel effect.

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Journal:  PLoS Pathog       Date:  2010-09-09       Impact factor: 6.823

8.  Aqueous and organic solvent-extracts of selected south African medicinal plants possess antimicrobial activity against drug-resistant strains of Helicobacter pylori: inhibitory and bactericidal potential.

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Journal:  Int J Mol Sci       Date:  2011-09-02       Impact factor: 5.923

9.  Anticonvulsant Activity of Extracts of Plectranthus barbatus Leaves in Mice.

Authors:  Luciana Cristina Borges Fernandes; Carlos Campos Câmara; Benito Soto-Blanco
Journal:  Evid Based Complement Alternat Med       Date:  2011-06-09       Impact factor: 2.629

10.  Improved pharmacokinetics and reduced toxicity of brucine after encapsulation into stealth liposomes: role of phosphatidylcholine.

Authors:  Jun Chen; Guo-jun Yan; Rong-rong Hu; Qian-wen Gu; Ming-lei Chen; Wei Gu; Zhi-peng Chen; Bao-chang Cai
Journal:  Int J Nanomedicine       Date:  2012-07-26
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