A prospective test of the stress-buffering model of depression in adolescent girls: no support once again.

The stress-buffering model posits that social support mitigates the relation between negative life events and onset of depression, but prospective studies have provided little support for this assertion. The authors sought to provide a more sensitive test of this model by addressing certain methodological and statistical limitations of past studies with prospective data from 496 adolescent girls. Deficits in peer support predicted increases in depressive symptoms, and negative life events predicted onset of depressive pathology. However, none of the 14 prospective tests provided support for the stress-buffering model despite sufficient power. Results provide scant support for the stress-buffering model and suggest that it might be time to shift attention to alternative multivariate models concerning these risk factors.