Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Advances in the early detection of Alzheimer's disease.

Literature DB >> 15298007

Advances in the early detection of Alzheimer's disease.

Peter J Nestor¹, Philip Scheltens, John R Hodges.

Abstract

The combination of an aging population and the promise, possibly in the near future, of disease-modifying therapies have made the characterization of the early stages of Alzheimer's disease (AD) a topic of major research interest. In this article we review recent progress in our understanding of the evolution of early AD with particular reference to the symptomatic pre-dementia stage designated 'mild cognitive impairment', emphasizing work on the early cognitive profile and associated neuroimaging studies.

Entities: Disease

Mesh：

Substances：
Biomarkers

Year: 2004 PMID： 15298007 DOI： 10.1038/nrn1433

Source DB: PubMed Journal: Nat Med ISSN： 1078-8956 Impact factor: 53.440

Keyword Cloud
Cited

101 in total

1. Increased regional cerebral glucose uptake in an APP/PS1 model of Alzheimer's disease.

Authors: Géraldine Poisnel; Anne-Sophie Hérard; Nadine El Tannir El Tayara; Emmanuel Bourrin; Andreas Volk; Frank Kober; Benoit Delatour; Thierry Delzescaux; Thomas Debeir; Thomas Rooney; Jésus Benavides; Philippe Hantraye; Marc Dhenain
Journal: Neurobiol Aging Date: 2011-11-12 Impact factor: 4.673

2. Hippocampal hyperactivation associated with cortical thinning in Alzheimer's disease signature regions in non-demented elderly adults.

Authors: Deepti Putcha; Michael Brickhouse; Kelly O'Keefe; Caroline Sullivan; Dorene Rentz; Gad Marshall; Brad Dickerson; Reisa Sperling
Journal: J Neurosci Date: 2011-11-30 Impact factor: 6.167

3. Metabolic syndrome and localization of white matter hyperintensities in the elderly population.

Authors: Florence Portet; Adam M Brickman; Yaakov Stern; Nikolaos Scarmeas; Jordan Muraskin; Frank A Provenzano; Claudine Berr; Alain Bonafé; Sylvaine Artero; Karen Ritchie; Tasnime N Akbaraly
Journal: Alzheimers Dement Date: 2012-06-06 Impact factor: 21.566

4. Selection of aptamers for amyloid beta-protein, the causative agent of Alzheimer's disease.

Authors: Farid Rahimi; Gal Bitan
Journal: J Vis Exp Date: 2010-05-13 Impact factor: 1.355

Review 5. Potential predictors of hippocampal atrophy in Alzheimer's disease.

Authors: Vikas Dhikav; Kuljeet Anand
Journal: Drugs Aging Date: 2011-01-01 Impact factor: 3.923

6. Hippocampal hyperactivation in presymptomatic familial Alzheimer's disease.

Authors: Yakeel T Quiroz; Andrew E Budson; Kim Celone; Adriana Ruiz; Randall Newmark; Gabriel Castrillón; Francisco Lopera; Chantal E Stern
Journal: Ann Neurol Date: 2010-12 Impact factor: 10.422

7. Near-infrared spectroscopy (NIRS) and vagus somatosensory evoked potentials (VSEP) in the early diagnosis of Alzheimer's disease: rationale, design, methods, and first baseline data of the Vogel study.

Authors: Thomas Polak; Martin J Herrmann; Laura D Müller; Julia B M Zeller; Andrea Katzorke; Matthias Fischer; Fabian Spielmann; Erik Weinmann; Leif Hommers; Martin Lauer; Andreas J Fallgatter; Jürgen Deckert
Journal: J Neural Transm (Vienna) Date: 2017-09-01 Impact factor: 3.575

Advances in the early detection of Alzheimer's disease.

1. Increased regional cerebral glucose uptake in an APP/PS1 model of Alzheimer's disease.

2. Hippocampal hyperactivation associated with cortical thinning in Alzheimer's disease signature regions in non-demented elderly adults.

3. Metabolic syndrome and localization of white matter hyperintensities in the elderly population.

4. Selection of aptamers for amyloid beta-protein, the causative agent of Alzheimer's disease.

Review 5. Potential predictors of hippocampal atrophy in Alzheimer's disease.

6. Hippocampal hyperactivation in presymptomatic familial Alzheimer's disease.

7. Near-infrared spectroscopy (NIRS) and vagus somatosensory evoked potentials (VSEP) in the early diagnosis of Alzheimer's disease: rationale, design, methods, and first baseline data of the Vogel study.

Review 8. Perturbations of neural circuitry in aging, mild cognitive impairment, and Alzheimer's disease.

Review 9. Brain glucose hypometabolism and oxidative stress in preclinical Alzheimer's disease.

Review 10. Extracellular Zn²⁺-Dependent Amyloid-β_1-42 Neurotoxicity in Alzheimer's Disease Pathogenesis.

Advances in the early detection of Alzheimer's disease.

1. Increased regional cerebral glucose uptake in an APP/PS1 model of Alzheimer's disease.

2. Hippocampal hyperactivation associated with cortical thinning in Alzheimer's disease signature regions in non-demented elderly adults.

3. Metabolic syndrome and localization of white matter hyperintensities in the elderly population.

4. Selection of aptamers for amyloid beta-protein, the causative agent of Alzheimer's disease.

Review 5. Potential predictors of hippocampal atrophy in Alzheimer's disease.

6. Hippocampal hyperactivation in presymptomatic familial Alzheimer's disease.

7. Near-infrared spectroscopy (NIRS) and vagus somatosensory evoked potentials (VSEP) in the early diagnosis of Alzheimer's disease: rationale, design, methods, and first baseline data of the Vogel study.

Review 8. Perturbations of neural circuitry in aging, mild cognitive impairment, and Alzheimer's disease.

Review 9. Brain glucose hypometabolism and oxidative stress in preclinical Alzheimer's disease.

Review 10. Extracellular Zn2+-Dependent Amyloid-β1-42 Neurotoxicity in Alzheimer's Disease Pathogenesis.

Review 10. Extracellular Zn²⁺-Dependent Amyloid-β_1-42 Neurotoxicity in Alzheimer's Disease Pathogenesis.