Literature DB >> 1529790

Modifications in tissue histamine levels in mice treated with chronic epicutaneous application of phorbol-12-myristate-13-acetate.

C Ponvert1, C Burtin, P Canu, J Paupe.   

Abstract

Chronic epicutaneous application of phorbol-12-myristate-13-acetate (PMA) on the right flank of C 57 BL/6 mice induces an inflammatory reaction and a selective increase in skin histamine level at the site of treatment. Tissue histamine levels were not increased at other sites such as contralateral skin, stomach rumen and skeletal muscle, and were decreased in stomach fundus and dorsal skin. These results are in agreement with the hypothesis that mast cells play a significant role in cutaneous inflammation induced by PMA.

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Year:  1992        PMID： 1529790     DOI： 10.1007/bf01997494

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  21 in total

1.  The presence of histamine in tissue mast cells.

Authors:  J F RILEY; G B WEST
Journal:  J Physiol       Date:  1953-06-29       Impact factor: 5.182

2.  The function and mechanism of promoters of carcinogenesis.

Authors:  R K Boutwell
Journal:  CRC Crit Rev Toxicol       Date:  1974-01

3.  Tissue histamine levels and mast cell numbers in tumour-bearing mice.

Authors:  L Galoppin; F Raynaud; C Ponvert; A Fray; P Scheinmann; G Lespinats; P Canu; C Burtin
Journal:  Agents Actions       Date:  1984-04

4.  Mast cells are important in the development of hypersensitivity pneumonitis. A study with mast-cell-deficient mice.

Authors:  H Takizawa; K Ohta; K Hirai; Y Misaki; T Horiuchi; N Kobayashi; J Shiga; T Miyamoto
Journal:  J Immunol       Date:  1989-09-15       Impact factor: 5.422

5.  Automated histamine analysis for in vitro allergy testing. I. A method utilizing allergen-induced histamine release from whole blood.

Authors:  R P Siraganian; M J Brodsky
Journal:  J Allergy Clin Immunol       Date:  1976-06       Impact factor: 10.793

6.  Cellular and vascular manifestations of cell-mediated immunity.

Authors:  H F Dvorak; S J Galli; A M Dvorak
Journal:  Hum Pathol       Date:  1986-02       Impact factor: 3.466

7.  An early component of delayed-type hypersensitivity mediated by T cells and mast cells.

Authors:  H van Loveren; R Meade; P W Askenase
Journal:  J Exp Med       Date:  1983-05-01       Impact factor: 14.307

8.  Mast cell-dependent amplification of an immunologically nonspecific inflammatory response. Mast cells are required for the full expression of cutaneous acute inflammation induced by phorbol 12-myristate 13-acetate.

Authors:  B K Wershil; T Murakami; S J Galli
Journal:  J Immunol       Date:  1988-04-01       Impact factor: 5.422

9.  Phorbol esters cause sequential activation and deactivation of complement receptors on polymorphonuclear leukocytes.

Authors:  S D Wright; B C Meyer
Journal:  J Immunol       Date:  1986-03-01       Impact factor: 5.422

10.  Phorbol 12-myristate 13-acetate-induced development of functionally active mast cells in W/Wv but not Sl/Sld genetically mast cell-deficient mice.

Authors:  J R Gordon; S J Galli
Journal:  Blood       Date:  1990-04-15       Impact factor: 22.113
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