Literature DB >> 15297543

Multicenter evaluation of a new screening test that detects Clostridium difficile in fecal specimens.

L Zheng1, S F Keller, D M Lyerly, R J Carman, C W Genheimer, C A Gleaves, S J Kohlhepp, S Young, S Perez, K Ye.   

Abstract

Clostridium difficile causes approximately 25% of nosocomial antibiotic-associated diarrheas and most cases of pseudomembranous colitis. We evaluated C. DIFF CHEK, a new screening test that detects glutamate dehydrogenase of C. difficile. Our results showed that this test was comparable to PCR in sensitivity and specificity and outperformed bacterial culture.

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Year:  2004        PMID： 15297543      PMCID： PMC497597          DOI： 10.1128/JCM.42.8.3837-3840.2004

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  20 in total

1.  Positive regulation of Clostridium difficile toxins.

Authors:  J S Moncrief; L A Barroso; T D Wilkins
Journal:  Infect Immun       Date:  1997-03       Impact factor: 3.441

2.  Comparison of toxinotyping and PCR ribotyping of Clostridium difficile strains and description of novel toxinotypes.

Authors:  Maja Rupnik; Jon S Brazier; Brian I Duerden; Miklavz Grabnar; Simon L J Stubbs
Journal:  Microbiology (Reading)       Date:  2001-02       Impact factor: 2.777

3.  Genetic characterization of toxin A-negative, toxin B-positive Clostridium difficile isolates by PCR.

Authors:  J S Moncrief; L Zheng; L M Neville; D M Lyerly
Journal:  J Clin Microbiol       Date:  2000-08       Impact factor: 5.948

4.  Primary symptomless colonisation by Clostridium difficile and decreased risk of subsequent diarrhoea.

Authors:  J K Shim; S Johnson; M H Samore; D Z Bliss; D N Gerding
Journal:  Lancet       Date:  1998-02-28       Impact factor: 79.321

5.  Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile.

Authors:  Lorraine Kyne; Mary Beth Hamel; Rajashekhar Polavaram; Ciarán P Kelly
Journal:  Clin Infect Dis       Date:  2001-12-17       Impact factor: 9.079

6.  Rapid detection of toxigenic Clostridium difficile from stool samples by a nested PCR of toxin B gene.

Authors:  R Alonso; C Muñoz; S Gros; D García de Viedma; T Peláez; E Bouza
Journal:  J Hosp Infect       Date:  1999-02       Impact factor: 3.926

Review 7.  The role of the clinical microbiology laboratory in the management of Clostridium difficile-associated diarrhea.

Authors:  L R Peterson; P J Kelly
Journal:  Infect Dis Clin North Am       Date:  1993-06       Impact factor: 5.982

8.  Survey of incidence of Clostridium difficile infection in Canadian hospitals and diagnostic approaches.

Authors:  M J Alfa; T Du; G Beda
Journal:  J Clin Microbiol       Date:  1998-07       Impact factor: 5.948

9.  Evaluation of a commercial latex test for Clostridium difficile for reactivity with C. difficile and cross-reactions with other bacteria.

Authors:  B L Miles; J A Siders; S D Allen
Journal:  J Clin Microbiol       Date:  1988-11       Impact factor: 5.948

10.  Characterization of cross-reactive proteins detected by Culturette Brand Rapid Latex Test for Clostridium difficile.

Authors:  D M Lyerly; D W Ball; J Toth; T D Wilkins
Journal:  J Clin Microbiol       Date:  1988-03       Impact factor: 5.948
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  21 in total

Review 1.  Molecular techniques for diagnosis of Clostridium difficile infection: systematic review and meta-analysis.

Authors:  John C O'Horo; Amy Jones; Matthew Sternke; Christopher Harper; Nasia Safdar
Journal:  Mayo Clin Proc       Date:  2012-07       Impact factor: 7.616

2.  Prospective multicenter evaluation of a new immunoassay and real-time PCR for rapid diagnosis of Clostridium difficile-associated diarrhea in hospitalized patients.

Authors:  Renate J van den Berg; Lesla S Bruijnesteijn van Coppenraet; Hendrik-Jan Gerritsen; Hubert P Endtz; Eric R van der Vorm; Ed J Kuijper
Journal:  J Clin Microbiol       Date:  2005-10       Impact factor: 5.948

3.  Laboratory testing considerations for C. difficile disease.

Authors:  David F Welch
Journal:  Proc (Bayl Univ Med Cent)       Date:  2006-01

4.  Effective detection of toxigenic Clostridium difficile by a two-step algorithm including tests for antigen and cytotoxin.

Authors:  John R Ticehurst; Deborah Z Aird; Lisa M Dam; Anita P Borek; John T Hargrove; Karen C Carroll
Journal:  J Clin Microbiol       Date:  2006-03       Impact factor: 5.948

5.  C. Diff Quik Chek complete enzyme immunoassay provides a reliable first-line method for detection of Clostridium difficile in stool specimens.

Authors:  Criziel D Quinn; Susan E Sefers; Wisal Babiker; Ying He; Romina Alcabasa; Charles W Stratton; Karen C Carroll; Yi-Wei Tang
Journal:  J Clin Microbiol       Date:  2009-12-02       Impact factor: 5.948

6.  Loop-mediated isothermal amplification compared to real-time PCR and enzyme immunoassay for toxigenic Clostridium difficile detection.

Authors:  Bobby L Boyanton; Preethi Sural; Caroline R Loomis; Christine Pesta; Laura Gonzalez-Krellwitz; Barbara Robinson-Dunn; Paul Riska
Journal:  J Clin Microbiol       Date:  2011-12-21       Impact factor: 5.948

7.  Clostridium difficile testing in the clinical laboratory by use of multiple testing algorithms.

Authors:  Susan M Novak-Weekley; Elizabeth M Marlowe; John M Miller; Joven Cumpio; Jim H Nomura; Paula H Vance; Alice Weissfeld
Journal:  J Clin Microbiol       Date:  2010-01-13       Impact factor: 5.948

8.  Comparison of nine commercially available Clostridium difficile toxin detection assays, a real-time PCR assay for C. difficile tcdB, and a glutamate dehydrogenase detection assay to cytotoxin testing and cytotoxigenic culture methods.

Authors:  Kerrie Eastwood; Patrick Else; André Charlett; Mark Wilcox
Journal:  J Clin Microbiol       Date:  2009-08-26       Impact factor: 5.948

9.  Yield of stool culture with isolate toxin testing versus a two-step algorithm including stool toxin testing for detection of toxigenic Clostridium difficile.

Authors:  Megan E Reller; Clara A Lema; Trish M Perl; Mian Cai; Tracy L Ross; Kathleen A Speck; Karen C Carroll
Journal:  J Clin Microbiol       Date:  2007-09-05       Impact factor: 5.948

10.  Comparison of BD GeneOhm Cdiff real-time PCR assay with a two-step algorithm and a toxin A/B enzyme-linked immunosorbent assay for diagnosis of toxigenic Clostridium difficile infection.

Authors:  Elizabeth J Kvach; David Ferguson; Paul F Riska; Marie L Landry
Journal:  J Clin Microbiol       Date:  2009-10-28       Impact factor: 5.948
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