BACKGROUND: An unusual case of cavernous hemangioma coexisting with venous angioma in the ipsilateral orbit is described. CASE: A 67-year-old woman had a mass in the lower eyelid of her right eye and proptosis. Imaging examinations showed two masses connected to each other in the extraconal space of the right orbit. OBSERVATIONS: Anterior orbitotomy was performed to remove the tumors. Histopathological evaluation of the anteriorly located tumor revealed cavernous hemangioma. The posteriorly located tumor was found to be a venous angioma. Endothelial cells in both tumors showed positive immunostaining for factor VIII-related antigen and smooth muscle actin. Immunoreactivity of smooth muscle actin was more prominent in the interstitium of the posteriorly located tumor. CONCLUSION: Coexistence of cavernous hemangioma and venous angioma in the same area suggests that they are a continuum and of the same origin. Copyright Japanese Ophthalmological Society 2004
BACKGROUND: An unusual case of cavernous hemangioma coexisting with venous angioma in the ipsilateral orbit is described. CASE: A 67-year-old woman had a mass in the lower eyelid of her right eye and proptosis. Imaging examinations showed two masses connected to each other in the extraconal space of the right orbit. OBSERVATIONS: Anterior orbitotomy was performed to remove the tumors. Histopathological evaluation of the anteriorly located tumor revealed cavernous hemangioma. The posteriorly located tumor was found to be a venous angioma. Endothelial cells in both tumors showed positive immunostaining for factor VIII-related antigen and smooth muscle actin. Immunoreactivity of smooth muscle actin was more prominent in the interstitium of the posteriorly located tumor. CONCLUSION: Coexistence of cavernous hemangioma and venous angioma in the same area suggests that they are a continuum and of the same origin. Copyright Japanese Ophthalmological Society 2004