Literature DB >> 15295251

Accidental ecstasy poisoning in a toddler.

Abian Montesdeoca Melian1, Guillermo Burillo-Putze, Candelaria Gonzalez Campo, Agustin Gonzalez Padron, Carlos Ormazabal Ramos.   

Abstract

A child of 14 months accidentally swallowed a portion of an Ecstasy pill. Forty minutes after ingestion, he started a generalized convulsion. He also presented hyperthermia (38 degrees C), hypertension, tachycardia (130 bpm), ventricular extrasystoles, tachypnea (50 rpm), and mydriasis. At the hospital 5 hours later, the urine levels of amphetamine/metamphetamine were >16 mg/L. He was treated with general support measures and benzodiazepines intravenously and admitted to the pediatric intensive care unit. During the first 12 hours, he continued with hypertension, tachycardia, and long periods of trigeminy, without hemodynamic repercussion. He was discharged fully recovered. Gas chromatography/mass spectrometry analysis (8 hours after ingestion) showed a serum level of 3,4 methylenedioximethylamphetamine (MDMA) of 0.591 mg/L. The 3 cases described in the literature have shown a good evolution of Ecstasy poisoning in toddlers and infants, despite an initial critical situation. Regarding adults, the toddler intoxication seems to present symptoms sooner (20 to 30 minutes), having as an initial manifestation convulsions. However, great care must be taken on accidental ingestion of these attractive design pills.

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Year:  2004        PMID: 15295251     DOI: 10.1097/01.pec.0000136072.37575.19

Source DB:  PubMed          Journal:  Pediatr Emerg Care        ISSN: 0749-5161            Impact factor:   1.454


  5 in total

1.  Accidental ecstasy intoxication in an 8-month-old infant.

Authors:  Corien W E van Rijswijk; Martin C J Kneyber; Frans B Plötz
Journal:  Intensive Care Med       Date:  2006-01-27       Impact factor: 17.440

Review 2.  A developmental comparison of the neurobehavioral effects of ecstasy (MDMA).

Authors:  Brian J Piper
Journal:  Neurotoxicol Teratol       Date:  2006-10-20       Impact factor: 3.763

Review 3.  Ecstasy intoxication as an unusual cause of epileptic seizures in young children.

Authors:  Steven Pauwels; Francis Lemmens; Kim Eerdekens; Joris Penders; Koen Poesen; Koen Desmet; Pieter Vermeersch
Journal:  Eur J Pediatr       Date:  2013-07-05       Impact factor: 3.183

4.  Oral administration of (+/-)3,4-methylenedioxymethamphetamine and (+)methamphetamine alters temperature and activity in rhesus macaques.

Authors:  Rebecca D Crean; Sophia A Davis; Michael A Taffe
Journal:  Pharmacol Biochem Behav       Date:  2007-04-03       Impact factor: 3.533

5.  Severe Ecstasy poisoning in an 8-month-old infant.

Authors:  Frank Eifinger; Bernhard Roth; Lars Kröner; Markus A Rothschild
Journal:  Eur J Pediatr       Date:  2007-09-26       Impact factor: 3.183

  5 in total

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