What is happening? Are the current acceptance criteria for therapeutic plasma adequate?

The main objective of this overview is to highlight the impact of new developments in the processing of plasma, on the quality, safety and efficacy fresh frozen plasma (FFP). Based on the currently available information, it is suggested that current guidelines need an urgent review to include more relevant criteria of acceptability for therapeutic plasma. Moreover additional streamlining of FFP production, using selective donor panel, will improve the uniformity of therapeutic plasma and lower the potential risks of transfusion reactions.