Literature DB >> 15294052

Insulin-like growth factor 1 and muscle growth: implication for satellite cell proliferation.

Shuichi Machida1, Frank W Booth.   

Abstract

Insulin-like growth factor 1 (IGF-1) has been shown to rescue the aging-related or inactivity-induced loss of muscle mass through the activation of satellite cells. However, the signalling pathways and the mechanism by which IGF-1 affects satellite cells have not been not completely identified. The purpose of the present review is to provide current understanding of the cellular and molecular events underlying IGF-1 induced proliferation of satellite cells.

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Year:  2004        PMID： 15294052     DOI： 10.1079/PNS2004354

Source DB:  PubMed          Journal:  Proc Nutr Soc        ISSN： 0029-6651            Impact factor:   6.297


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