Literature DB >> 15293979

Diabetes mellitus: pathogenesis and treatment strategies.

Jay S Skyler1.   

Abstract

This article introduces the disease state of diabetes mellitus and provides a background of the impact of the disease on the population, its biology and pathophysiology, and the current treatment strategies for treating diabetes. Copyright 2004 American Chemical Society

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15293979     DOI： 10.1021/jm0306273

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


  33 in total

1.  Characterization of CD4+ T cells specific for glutamic acid decarboxylase (GAD65) and proinsulin in a patient with stiff-person syndrome but without type 1 diabetes.

Authors:  Arno Hänninen; Merja Soilu-Hänninen; Christiane S Hampe; Angie Deptula; Kelly Geubtner; Jorma Ilonen; Mikael Knip; Helena Reijonen
Journal:  Diabetes Metab Res Rev       Date:  2010-05       Impact factor: 4.876

2.  Design of Potent and Orally Active GPR119 Agonists for the Treatment of Type II Diabetes.

Authors:  Ping Liu; Zhiyong Hu; Byron G DuBois; Christopher R Moyes; David N Hunter; Cheng Zhu; Nam Fung Kar; Yuping Zhu; Joie Garfunkle; Ling Kang; Gary Chicchi; Anka Ehrhardt; Andrea Woods; Toru Seo; Morgan Woods; Margaret van Heek; Karen H Dingley; Jianmei Pang; Gino M Salituro; Joyce Powell; Jenna L Terebetski; Viktor Hornak; Louis-Charles Campeau; Joe Lamberson; Fez Ujjainwalla; Michael Miller; Andrew Stamford; Harold B Wood; Timothy Kowalski; Ravi P Nargund; Scott D Edmondson
Journal:  ACS Med Chem Lett       Date:  2015-07-10       Impact factor: 4.345

3.  Islet beta-cell-specific T cells can use different homing mechanisms to infiltrate and destroy pancreatic islets.

Authors:  Arno Hänninen; Rita Nurmela; Mikael Maksimow; Jarkko Heino; Sirpa Jalkanen; Christian Kurts
Journal:  Am J Pathol       Date:  2007-01       Impact factor: 4.307

4.  Identification of Novel, Structurally Diverse, Small Molecule Modulators of GPR119.

Authors:  Ainhoa Nieto; Virneliz Fernández-Vega; Timothy P Spicer; Emmanuel Sturchler; Pramisha Adhikari; Nicole Kennedy; Sean Mandat; Peter Chase; Louis Scampavia; Thomas Bannister; Peter Hodder; Patricia H McDonald
Journal:  Assay Drug Dev Technol       Date:  2018-07       Impact factor: 1.738

5.  American ginseng berry juice intake reduces blood glucose and body weight in ob/ob mice.

Authors:  J T Xie; C Z Wang; M Ni; J A Wu; S R Mehendale; H H Aung; A Foo; C S Yuan
Journal:  J Food Sci       Date:  2007-10       Impact factor: 3.167

6.  Can Roux-en-Y gastric bypass provide a lifelong solution for diabetes mellitus?

Authors:  Abdulzahra Hussain; Hind Mahmood; Shamsi El-Hasani
Journal:  Can J Surg       Date:  2009-12       Impact factor: 2.089

7.  Theoretical study on the molecular and electronic properties of some substances used for diabetes mellitus treatment.

Authors:  Vinicius G Maltarollo; Paula Homem-de-Mello; Kathia M Honório
Journal:  J Mol Model       Date:  2009-12-12       Impact factor: 1.810

8.  Pharmacotherapy-Based Problems in the Management of Diabetes Mellitus: Needs Much More to be Done!

Authors:  N Ali; Swa Shah; J Khan; S Rehman; M Imran; I Hussian; N Shehbaz; H Jamshed; S Khan
Journal:  J Young Pharm       Date:  2010-07

9.  Derivatives of (phenylsulfonamido-methyl)nicotine and (phenylsulfonamido-methyl)thiazole as novel 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: synthesis and biological activities in vitro.

Authors:  Xu Zhang; Yang Zhou; Yu Shen; Li-li Du; Jun-hua Chen; Ying Leng; Jian-hua Shen
Journal:  Acta Pharmacol Sin       Date:  2009-08-24       Impact factor: 6.150

10.  Proteome, phosphoproteome, and hydroxyproteome of liver mitochondria in diabetic rats at early pathogenic stages.

Authors:  Wen-Jun Deng; Song Nie; Jie Dai; Jia-Rui Wu; Rong Zeng
Journal:  Mol Cell Proteomics       Date:  2009-08-23       Impact factor: 5.911
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.