Literature DB >> 15293001

[Multimodal diagnosis of multiple and heterogeneous liver lesions in a young patient].

F Kiessling1, H-P Schlemmer.   

Abstract

The classification of liver lesions is often problematic in particular if they are multiple and show an heterogeneous shape. Here we report of a young patient with multiple liver lesions of up to 3 cm size. Using ultrasound, the lesions were hyper-, hypoechogen or mixed. In serial contrast enhanced CT scans some of the lesions showed the typical enhancement pattern of hemangiomas, however, the diagnosis could still not be faithfully determined for all lesions. Therefore, the patient was conducted to contrast enhanced MRI (Gd-DTPA and MnDPDP). While with Gd-DTPA some of the lesions showed a strong enhancement, they remained hypointense after administration of MnDPDP. Finally to exclude a metastatic disease a (99m)Tc-erythrocyte SPECT was performed confirming the diagnosis of hemangiomas for most of the lesions. Diagnosis was not assessed by biopsy because this would only clarify the diagnosis for one or few of the lesions. The patient was subsequently followed up for 3 years and all lesions remained unchanged. This case clearly illustrates the difficulty to get a certain diagnosis of multiple liver lesions with heterogeneous appearance despite the multimodal diagnostic conduct.

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Mesh:

Year:  2005        PMID: 15293001     DOI: 10.1007/s00117-004-1088-7

Source DB:  PubMed          Journal:  Radiologe        ISSN: 0033-832X            Impact factor:   0.635


  12 in total

1.  Hepatic hemangiomas vs metastases: MR differentiation at 1.5 T.

Authors:  D M Lombardo; M E Baker; C E Spritzer; R Blinder; W Meyers; R J Herfkens
Journal:  AJR Am J Roentgenol       Date:  1990-07       Impact factor: 3.959

2.  Planar and SPECT Tc-99m red blood cell imaging in hepatic cavernous hemangiomas and other hepatic lesions.

Authors:  C Intenzo; S Kim; M Madsen; A Desai; C Park
Journal:  Clin Nucl Med       Date:  1988-04       Impact factor: 7.794

3.  Clinical manifestations of hereditary hemorrhagic telangiectasia.

Authors:  P J Reilly; T T Nostrant
Journal:  Am J Gastroenterol       Date:  1984-05       Impact factor: 10.864

4.  Progressive development of diffuse liver hemangiomatosis.

Authors:  F S Lehmann; C Beglinger; K Schnabel; L Terracciano
Journal:  J Hepatol       Date:  1999-05       Impact factor: 25.083

5.  Diagnostic efficacy of MnDPDP in MR imaging of the liver. A phase III multicentre study.

Authors:  C Wang; H Ahlström; S Ekholm; H Fagertun; M Hellström; A Hemmingsson; S Holtås; B Isberg; E Jonnson; M Lönnemark-Magnusson; S McGill; N O Wallengren; L Westman
Journal:  Acta Radiol       Date:  1997-07       Impact factor: 1.701

6.  Improved detection of small cavernous hemangiomas of the liver with high-resolution three-headed SPECT.

Authors:  H A Ziessman; P M Silverman; J Patterson; B Harkness; F H Fahey; R K Zeman; J W Keyes
Journal:  J Nucl Med       Date:  1991-11       Impact factor: 10.057

7.  Differentiation between multiple liver hemangiomas and liver metastases of gastrinomas: value of enhanced MRI.

Authors:  J F Berger; J P Laissy; O Limot; M C Henry-Feugeas; G Cadiot; M Mignon; E Schouman-Claeys
Journal:  J Comput Assist Tomogr       Date:  1996 May-Jun       Impact factor: 1.826

8.  Hepatic hemangiomas: a multi-institutional study of appearance on T2-weighted and serial gadolinium-enhanced gradient-echo MR images.

Authors:  R C Semelka; E D Brown; S M Ascher; R H Patt; A S Bagley; W Li; R R Edelman; J P Shoenut; J J Brown
Journal:  Radiology       Date:  1994-08       Impact factor: 11.105

9.  Hepatic cavernous hemangiomas: simple diagnostic sign with dynamic bolus CT.

Authors:  S F Quinn; G G Benjamin
Journal:  Radiology       Date:  1992-02       Impact factor: 11.105

10.  CT of giant cavernous hemangioma.

Authors:  J C Scatarige; J M Kenny; E K Fishman; F H Herlong; S S Siegelman
Journal:  AJR Am J Roentgenol       Date:  1987-07       Impact factor: 3.959

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