| Literature DB >> 15291470 |
Mary W Ndung'u1, Bakari Kaoneka, Ahmed Hassanali, Wilber Lwande, Antony M Hooper, Francis Tayman, Oliver Zerbe, Baldwyn Torto.
Abstract
The crude methanol extracts of the root barks of Turraea wakefieldii and Turraea floribunda were found to show mosquito larvicidal activity against third-instar larvae of Anopheles gambiae sensu stricto. Four new limonoids comprising a vilasininoid 1 and three havanensinoids 2-4 were isolated from the chloroform fractions of the methanol extracts of T. wakefieldii and T. floribunda, respectively. The structures of the compounds were elucidated by NMR spectroscopy. Compounds 1, 2, and 4 had LD50 values of 7.1, 4.0, and 3.6 ppm, respectively, and were more potent than azadirachtin, which had an LD50 value of 57.1 ppm when tested against larvae of A. gambiae.Entities:
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Year: 2004 PMID： 15291470 DOI： 10.1021/jf049474y
Source DB: PubMed Journal: J Agric Food Chem ISSN： 0021-8561 Impact factor: 5.279