Literature DB >> 15290883

Acute effects of sildenafil on Humphrey visual field and intraocular pressure.

Sitki Samet Ermis1, Umit Ubeyt Inan, Murat Samli, Faruk Ozturk.   

Abstract

PURPOSE: To evaluate the effects of sildenafil on visual field and intraocular pressure in a group of healthy subjects.
METHODS: Twenty-eight healthy male volunteers with normal eyes were included in the study. Visual field examinations were performed using FASTPAC 30-2 program (white-on-white and blue-on-yellow) with the Humphrey field analyzer before and one hour after receiving oral 50 and 100 mg sildenafil citrate.
RESULTS: The mean age was 51.1 +/- 8.9 years. Mean deviation, pattern standard deviation, short-term fluctuation and corrected pattern standard deviation did not differ significantly among tests both in white-on-white and blue-on-yellow visual field examinations. Changes in intraocular pressure were not statistically significant.
CONCLUSIONS: No significant effect of sildenafil was seen on visual field and intraocular pressure in healthy subjects.

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Year:  2004        PMID: 15290883     DOI: 10.1023/b:inte.0000031735.45526.1c

Source DB:  PubMed          Journal:  Int Ophthalmol        ISSN: 0165-5701            Impact factor:   2.031


  17 in total

1.  Ocular safety of Viagra, (sildenafil citrate).

Authors:  A M Laties; F T Fraunfelder
Journal:  Trans Am Ophthalmol Soc       Date:  1999

2.  Effects of sildenafil, a type-5 cGMP phosphodiesterase inhibitor, and papaverine on cyclic GMP and cyclic AMP levels in the rabbit corpus cavernosum in vitro.

Authors:  J Y Jeremy; S A Ballard; A M Naylor; M A Miller; G D Angelini
Journal:  Br J Urol       Date:  1997-06

3.  Subjective visual halos after sildenafil (Viagra) administration: Electroretinographic evaluation.

Authors:  C B Gabrieli; F Regine; E M Vingolo; E Rispoli; A Fabbri; A Isidori
Journal:  Ophthalmology       Date:  2001-05       Impact factor: 12.079

Review 4.  Sildenafil (Viagra) and ophthalmology.

Authors:  M F Marmor; R Kessler
Journal:  Surv Ophthalmol       Date:  1999 Sep-Oct       Impact factor: 6.048

5.  Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes.

Authors:  S A Ballard; C J Gingell; K Tang; L A Turner; M E Price; A M Naylor
Journal:  J Urol       Date:  1998-06       Impact factor: 7.450

6.  Effect of sildenafil citrate (Viagra) on retinal blood vessel diameter.

Authors:  Juan E Grunwald; Tatyana Metelitsina; Lili Grunwald
Journal:  Am J Ophthalmol       Date:  2002-06       Impact factor: 5.258

7.  Acute effects of sildenafil (viagra) on blue-on-yellow and white-on-white Humphrey perimetry.

Authors:  T J McCulley; B L Lam; M F Marmor; K B Hoffman; J K Luu; W J Feuer
Journal:  J Neuroophthalmol       Date:  2000-12       Impact factor: 3.042

8.  A double-blind placebo-controlled evaluation of the acute effects of sildenafil citrate (Viagra) on visual function in subjects with early-stage age-related macular degeneration.

Authors:  David G Birch; Steven M Toler; William H Swanson; Gary E Fish; Alan M Laties
Journal:  Am J Ophthalmol       Date:  2002-05       Impact factor: 5.258

9.  No clinically important effects on intraocular pressure after short-term administration of sildenafil citrate (Viagra).

Authors:  T Yajima; Y Yajima; N Koppiker; J E Grunwald; A M Laties
Journal:  Am J Ophthalmol       Date:  2000-05       Impact factor: 5.258

10.  Sildenafil increases ocular perfusion.

Authors:  G Paris; W E Sponsel; S S Sandoval; W R Elliott; Y Trigo; D K Sanford; J M Harison
Journal:  Int Ophthalmol       Date:  2001       Impact factor: 2.031

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  3 in total

Review 1.  Precautions and Monitoring of Patients Taking Phosphodiesterase Type 5 Inhibitors Who are at Risk of Increased Intraocular Pressure.

Authors:  Joshua C Baker; Robert Fintelmann; Roohollah Sharifi; Mary Lee
Journal:  Drugs Aging       Date:  2019-11       Impact factor: 3.923

Review 2.  Phosphodiesterase Type 5 Inhibitors and Visual Side Effects: A Narrative Review.

Authors:  Francisco Barroso; João Crispim Ribeiro; Eduardo P Miranda
Journal:  J Ophthalmic Vis Res       Date:  2021-04-29

3.  Effect of periodic sildenafil dosage on intraocular pressure in patients with erectile dysfunction.

Authors:  Alireza Nazari; Yousof Taghavi Tabrizi; Mohammadreza Mokhtaree
Journal:  Electron Physician       Date:  2017-09-25
  3 in total

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