| Literature DB >> 15288923 |
P R Wakeley1, J L E Turner, G Ibata, D P King, T Sandvik, P Howard, T W Drew.
Abstract
Two genotypes of bovine viral diarrhoea virus (BVDV) are recognised. Type 2 was first recognised when virulent strains caused significant losses among cattle in North America. Subsequently, BVDV type 2 has been found in many other countries, but recent studies have shown that only type 1 BVDV is circulating in the UK herds (sheep and cattle) with type 1a predominating. During routine genotyping of UK BVDV isolates, a type 2 isolate was identified. Phylogenetic analysis of the 5'-untranslated region of the viral genome showed it to be a BVDV type 2a, most similar to a low virulent US strain of BVDV type 2. Antigenic typing with a panel of monoclonal antibodies verified this classification. This is the first confirmed isolation of BVDV type 2 found circulating in the UK.Entities:
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Year: 2004 PMID： 15288923 DOI： 10.1016/j.vetmic.2004.05.005
Source DB: PubMed Journal: Vet Microbiol ISSN： 0378-1135 Impact factor: 3.293