| Literature DB >> 1528710 |
P G Krugers Dagneaux1, C P Loohuis, J T Klein Elhorst, T S Van der Veer.
Abstract
A simple, selective and quantitative estimation of tranylcypromine using liquid chromatography and electrochemical detection with apomorphine as internal standard in human plasma is described. Sample preparation is done by liquid-liquid extraction. The absolute mean recovery of apomorphine is 95%, the recovery of tranylcypromine is 81%. This method gives a simple estimation method to assay plasma concentrations of tranylcypromine in the therapeutic range (5-200 ng/ml) with good reproducibility and linearity.Entities:
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Year: 1992 PMID： 1528710 DOI： 10.1007/bf01980481
Source DB: PubMed Journal: Pharm Weekbl Sci ISSN： 0167-6555