Literature DB >> 15287075

Evaluation of the gastric antiulcerogenic effects of Portulaca oleracea L. extracts in mice.

Gholamreza Karimi1, Hossein Hosseinzadeh, Negin Ettehad.   

Abstract

Portulaca oleracea is commonly used in Iranian folk medicine. The aqueous and ethanolic extracts were studied in mice for their ability to inhibit gastric lesions induced by HCl or absolute ethanol. In addition, their effects on gastric acid secretion were measured. Both extracts showed a dose-dependent reduction in severity of ulcers. The highest dose of extracts exerted similar activity to sucralfate. The oral and intraperitoneal administration of extracts reduced the gastric acidity in pylorus-ligated mice. These results suggest that Portulaca oleracea has gastroprotective action and validates its use in folk medicine for gastrointestinal diseases.

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Year:  2004        PMID： 15287075     DOI： 10.1002/ptr.1463

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  10 in total

1.  Protective effects of ethanol extract from Portulaca oleracea L on dextran sulphate sodium-induced mice ulcerative colitis involving anti-inflammatory and antioxidant.

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Journal:  J Ethnobiol Ethnomed       Date:  2006-10-13       Impact factor: 2.733

5.  A Comparison between Water and Ethanol Extracts of Rumex acetosa for Protective Effects on Gastric Ulcers in Mice.

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6.  Assessment of some Herbal Drugs for Prophylaxis of Peptic Ulcer.

Authors:  Ahmed A Gohar; Ahmed A Zaki
Journal:  Iran J Pharm Res       Date:  2014       Impact factor: 1.696

Review 7.  Portulaca oleracea L.: a review of phytochemistry and pharmacological effects.

Authors:  Yan-Xi Zhou; Hai-Liang Xin; Khalid Rahman; Su-Juan Wang; Cheng Peng; Hong Zhang
Journal:  Biomed Res Int       Date:  2015-01-26       Impact factor: 3.411

Review 8.  Traditional Persian topical medications for gastrointestinal diseases.

Authors:  Laleh Dehghani Tafti; Seyyed Mahyar Shariatpanahi; Mahmoud Mahdavi Damghani; Behjat Javadi
Journal:  Iran J Basic Med Sci       Date:  2017-03       Impact factor: 2.699

9.  Quantitative study of medicinal plants used by the communities residing in Koh-e-Safaid Range, northern Pakistani-Afghan borders.

Authors:  Wahid Hussain; Lal Badshah; Manzoor Ullah; Maroof Ali; Asghar Ali; Farrukh Hussain
Journal:  J Ethnobiol Ethnomed       Date:  2018-04-25       Impact factor: 2.733

10.  Evaluation of the Therapeutic Effects of the Hydroethanolic Extract of Portulaca oleracea on Surgical-Induced Peritoneal Adhesion.

Authors:  Ali Jaafari; Vafa Baradaran Rahimi; Nasser Vahdati-Mashhadian; Roghayeh Yahyazadeh; Alireza Ebrahimzadeh-Bideskan; Maede Hasanpour; Mehrdad Iranshahi; Sajjad Ehtiati; Hamed Rajabi; Mohammadreza Mahdinezhad; Hassan Rakhshandeh; Vahid Reza Askari
Journal:  Mediators Inflamm       Date:  2021-07-31       Impact factor: 4.711
  10 in total

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