Literature DB >> 15286861

[Ophthalmological findings in HIV infected patients in the post-HAART (Highly Active Anti-retroviral Therapy) era, compared to the pre-HAART era].

Rafael Fávaro Arruda1, Cristina Muccioli, Rubens Belfort.   

Abstract

BACKGROUND: To determine the frequency of the ophthalmological findings in Human Immunodeficience Virus (HIV) infected patients in the post-HAART (Highly Active Anti-retroviral Therapy) era and to compare it to data from the Federal University of São Paulo in the pre-HAART era10,11.
METHODS: Charts from 200 consecutive patients examined from May 2000 to February 2001 were reviewed.
RESULTS: From the total of 200 patients, 84 (42%) presented ophthalmological findings related to HIV infection in the first ocular examination: 36 (18%) with Cytomegalovirus retinitis (9 active and 27 inactive), 22 (11%) with ocular toxoplasmosis, (9 active and 13 inactive), 15 (7.5%) with retinal detachment (10 secondary to CMV retinitis, 3 to ocular toxoplasmosis and 2 not determined), 8 (4%) with cataract (5 secondary to CMV retinitis, 1 to ocular toxoplasmosis and 2 not determined), 8 (4%) with cotton wool spots, 6 (3%) with acute retinal necrosis (4 active and 2 inactive) and 3 (1.5%) with intersticial keratitis. All patients with acute retinal necrosis showed T CD4 cells under 100 cells/microL.
CONCLUSION: The authors identified in the post-HAART era, rise on number of patients with normal ophthalmologic exam and decreased number of cases of CMV retinitis and ocular toxoplasmosis when compared to the pre-HAART era.

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Year:  2004        PMID: 15286861     DOI: 10.1590/s0104-42302004000200029

Source DB:  PubMed          Journal:  Rev Assoc Med Bras (1992)        ISSN: 0104-4230            Impact factor:   1.209


  2 in total

1.  Vitreal pharmacokinetics of peptide-transporter-targeted prodrugs of ganciclovir in conscious animals.

Authors:  Kumar G Janoria; Sai H S Boddu; Subramanian Natesan; Ashim K Mitra
Journal:  J Ocul Pharmacol Ther       Date:  2010-06       Impact factor: 2.671

Review 2.  Anterior segment manifestations of human immunodeficiency virus/acquired immune deficiency syndrome.

Authors:  Jyotirmay Biswas; S Sudharshan
Journal:  Indian J Ophthalmol       Date:  2008 Sep-Oct       Impact factor: 1.848

  2 in total

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