Literature DB >> 15286734

Drug repositioning: identifying and developing new uses for existing drugs.

Ted T Ashburn1, Karl B Thor.   

Abstract

Mesh：

Year:  2004        PMID： 15286734     DOI： 10.1038/nrd1468

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  861 in total

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2.  A novel two-stage, transdisciplinary study identifies digoxin as a possible drug for prostate cancer treatment.

Authors:  Elizabeth A Platz; Srinivasan Yegnasubramanian; Jun O Liu; Curtis R Chong; Joong Sup Shim; Stacey A Kenfield; Meir J Stampfer; Walter C Willett; Edward Giovannucci; William G Nelson
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3.  Drug repositioning using disease associated biological processes and network analysis of drug targets.

Authors:  Sachin Mathur; Deendayal Dinakarpandian
Journal:  AMIA Annu Symp Proc       Date:  2011-10-22

4.  Associating Drugs, Targets and Clinical Outcomes into an Integrated Network Affords a New Platform for Computer-Aided Drug Repurposing.

Authors:  Tudor I Oprea; Sonny Kim Nielsen; Oleg Ursu; Jeremy J Yang; Olivier Taboureau; Stephen L Mathias; Lrene Kouskoumvekaki; Larry A Sklar; Cristian G Bologa
Journal:  Mol Inform       Date:  2011-03-14       Impact factor: 3.353

5.  Target identification by chromatographic co-elution: monitoring of drug-protein interactions without immobilization or chemical derivatization.

Authors:  Janet N Y Chan; Dajana Vuckovic; Lekha Sleno; Jonathan B Olsen; Oxana Pogoutse; Pierre Havugimana; Johannes A Hewel; Navgeet Bajaj; Yale Wang; Marcel F Musteata; Corey Nislow; Andrew Emili
Journal:  Mol Cell Proteomics       Date:  2012-02-22       Impact factor: 5.911

6.  Virtual target screening: validation using kinase inhibitors.

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Journal:  J Chem Inf Model       Date:  2012-07-23       Impact factor: 4.956

7.  Drug discovery in a multidimensional world: systems, patterns, and networks.

Authors:  Joel T Dudley; Eric Schadt; Marina Sirota; Atul J Butte; Euan Ashley
Journal:  J Cardiovasc Transl Res       Date:  2010-07-31       Impact factor: 4.132

8.  Naproxen induces cell-cycle arrest and apoptosis in human urinary bladder cancer cell lines and chemically induced cancers by targeting PI3K.

Authors:  Mi-Sung Kim; Jong-Eun Kim; Do Young Lim; Zunnan Huang; Hanyong Chen; Alyssa Langfald; Ronald A Lubet; Clinton J Grubbs; Zigang Dong; Ann M Bode
Journal:  Cancer Prev Res (Phila)       Date:  2013-12-10

9.  The STAT3 inhibitor pimozide impedes cell proliferation and induces ROS generation in human osteosarcoma by suppressing catalase expression.

Authors:  Nan Cai; Wei Zhou; Lan-Lan Ye; Jun Chen; Qiu-Ni Liang; Gang Chang; Jia-Jie Chen
Journal:  Am J Transl Res       Date:  2017-08-15       Impact factor: 4.060

10.  Drug repurposing screen reveals FDA-approved inhibitors of human HMG-CoA reductase and isoprenoid synthesis that block Cryptosporidium parvum growth.

Authors:  Kovi Bessoff; Adam Sateriale; K Kyungae Lee; Christopher D Huston
Journal:  Antimicrob Agents Chemother       Date:  2013-02-04       Impact factor: 5.191
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