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Literature DB >> 15286725

Fibrotic disease and the T(H)1/T(H)2 paradigm.

Thomas A Wynn¹.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 2004 PMID： 15286725 PMCID： PMC2702150 DOI： 10.1038/nri1412

Source DB: PubMed Journal: Nat Rev Immunol ISSN： 1474-1733 Impact factor: 53.106

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128 in total

1. An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response.

Authors: M G Chiaramonte; D D Donaldson; A W Cheever; T A Wynn
Journal: J Clin Invest Date: 1999-09 Impact factor: 14.808

2. Th1/Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells.

Authors: M Munder; K Eichmann; J M Morán; F Centeno; G Soler; M Modolell
Journal: J Immunol Date: 1999-10-01 Impact factor: 5.422

3. Cooperation between Th1 and Th2 cells in a murine model of eosinophilic airway inflammation.

Authors: D A Randolph; R Stephens; C J Carruthers; D D Chaplin
Journal: J Clin Invest Date: 1999-10 Impact factor: 14.808

4. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production.

Authors: Z Zhu; R J Homer; Z Wang; Q Chen; G P Geba; J Wang; Y Zhang; J A Elias
Journal: J Clin Invest Date: 1999-03 Impact factor: 14.808

5. Critical roles for IL-4, IL-5, and eosinophils in chronic skin allograft rejection.

Authors: A Le Moine; V Flamand; F X Demoor; J C Noël; M Surquin; R Kiss; M A Nahori; M Pretolani; M Goldman; D Abramowicz
Journal: J Clin Invest Date: 1999-06 Impact factor: 14.808

6. Effects of interferon-gamma on expression of cell surface receptors for collagen and deposition of newly synthesized collagen by cultured human lung fibroblasts.

Authors: J G Clark; T F Dedon; E A Wayner; W G Carter
Journal: J Clin Invest Date: 1989-05 Impact factor: 14.808

7. The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis.

Authors: J S Munger; X Huang; H Kawakatsu; M J Griffiths; S L Dalton; J Wu; J F Pittet; N Kaminski; C Garat; M A Matthay; D B Rifkin; D Sheppard
Journal: Cell Date: 1999-02-05 Impact factor: 41.582

8. The pathogenesis of schistosomiasis is controlled by cooperating IL-10-producing innate effector and regulatory T cells.

Authors: Matthias Hesse; Ciriaco A Piccirillo; Yasmine Belkaid; Jeannette Prufer; Margaret Mentink-Kane; Mary Leusink; Allen W Cheever; Ethan M Shevach; Thomas A Wynn
Journal: J Immunol Date: 2004-03-01 Impact factor: 5.422

9. IL-13 activates a mechanism of tissue fibrosis that is completely TGF-beta independent.

Authors: Mallika Kaviratne; Matthias Hesse; Mary Leusink; Allen W Cheever; Stephen J Davies; James H McKerrow; Lalage M Wakefield; John J Letterio; Thomas A Wynn
Journal: J Immunol Date: 2004-09-15 Impact factor: 5.422

10. P-selectin suppresses hepatic inflammation and fibrosis in mice by regulating interferon gamma and the IL-13 decoy receptor.

Authors: Thomas A Wynn; Matthias Hesse; Netanya G Sandler; Mallika Kaviratne; Karl F Hoffmann; Monica G Chiaramonte; Rachael Reiman; Allen W Cheever; Joseph P Sypek; Margaret M Mentink-Kane
Journal: Hepatology Date: 2004-03 Impact factor: 17.425

587 in total

1. Protective role of NKT cells and macrophage M2-driven phenotype in bleomycin-induced pulmonary fibrosis.

Authors: Felipe Grabarz; Cristhiane Favero Aguiar; Matheus Correa-Costa; Tárcio Teodoro Braga; Meire I Hyane; Vinícius Andrade-Oliveira; Maristella Almeida Landgraf; Niels Olsen Saraiva Câmara
Journal: Inflammopharmacology Date: 2017-08-04 Impact factor: 4.473

Review 2. Fibrosis: ultimate and proximate causes.

Authors: Victor J Thannickal; Yong Zhou; Amit Gaggar; Steven R Duncan
Journal: J Clin Invest Date: 2014-11-03 Impact factor: 14.808

3. p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.

Authors: Céline Cudejko; Kristiaan Wouters; Lucía Fuentes; Sarah Anissa Hannou; Charlotte Paquet; Kadiombo Bantubungi; Emmanuel Bouchaert; Jonathan Vanhoutte; Sébastien Fleury; Patrick Remy; Anne Tailleux; Giulia Chinetti-Gbaguidi; David Dombrowicz; Bart Staels; Réjane Paumelle
Journal: Blood Date: 2011-06-02 Impact factor: 22.113

Fibrotic disease and the T(H)1/T(H)2 paradigm.

1. An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response.

2. Th1/Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells.

3. Cooperation between Th1 and Th2 cells in a murine model of eosinophilic airway inflammation.

4. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production.

5. Critical roles for IL-4, IL-5, and eosinophils in chronic skin allograft rejection.

6. Effects of interferon-gamma on expression of cell surface receptors for collagen and deposition of newly synthesized collagen by cultured human lung fibroblasts.

7. The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis.

8. The pathogenesis of schistosomiasis is controlled by cooperating IL-10-producing innate effector and regulatory T cells.

9. IL-13 activates a mechanism of tissue fibrosis that is completely TGF-beta independent.

10. P-selectin suppresses hepatic inflammation and fibrosis in mice by regulating interferon gamma and the IL-13 decoy receptor.

1. Protective role of NKT cells and macrophage M2-driven phenotype in bleomycin-induced pulmonary fibrosis.

Review 2. Fibrosis: ultimate and proximate causes.

3. p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.

Review 4. Functional role of chemokines in liver disease models.

Review 5. Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils.

6. Cross-talk within the tumor microenvironment mediates Th2-type inflammation in pancreatic cancer.

Review 7. Investigational approaches to therapies for idiopathic pulmonary fibrosis.

8. Reprogrammed fibrocytes induce a mixed Th1/Th2 cytokine response of naïve CD4(+) T cells.

Review 9. Molecular imaging of fibrosis: recent advances and future directions.

Review 10. Host responses in tissue repair and fibrosis.