| Literature DB >> 15282704 |
Axel Kleespies1, Markus Guba, Karl-Walter Jauch, Christiane J Bruns.
Abstract
Vascular endothelial growth factor (VEGF) plays a crucial role in angiogenesis of many solid malignancies. The influence of angiogenesis and VEGF expression on progression and recurrence of esophageal cancer has been investigated over the last years. This article reviews the prognostic significance of VEGF expression, microvessel density (MVD), and lymphangiogenic factors in squamous cell carcinoma (SCC), Barrett's dysplasia, and adenocarcinoma (AC) of the esophagus, their predictive value for treatment response to chemo-radiotherapy and new anti-angiogenic treatment strategies. Copyright 2004 Wiley-Liss, Inc.Entities:
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Year: 2004 PMID: 15282704 DOI: 10.1002/jso.20070
Source DB: PubMed Journal: J Surg Oncol ISSN: 0022-4790 Impact factor: 3.454