Literature DB >> 15281757

Synthesis of the sialic acid (-)-KDN and certain epimers from (-)-3-dehydroshikimic acid or (-)-quinic acid.

Martin G Banwell1, Natasha L Hungerford, Katrina A Jolliffe.   

Abstract

(-)-3-Dehydroshikimic acid (3-DHS, 4), a C(7)-building block now available in large quantity from corn syrup, has been converted into the sialic acid (-)-KDN (3) as well as its C-7- and C-8-epimers. (-)-Quinic acid can be used for the same purpose. [structure: see text]

Entities:  

Year:  2004        PMID: 15281757     DOI: 10.1021/ol049048y

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Practical synthesis of 2-keto-3-deoxy-D-glycero-D-galactononulosonic acid (KDN).

Authors:  David Crich; Chandrasekhar Navuluri
Journal:  Org Lett       Date:  2011-11-09       Impact factor: 6.005

Review 2.  KDN (deaminated neuraminic acid): dreamful past and exciting future of the newest member of the sialic acid family.

Authors:  Sadako Inoue; Ken Kitajima
Journal:  Glycoconj J       Date:  2006-07       Impact factor: 2.916

  2 in total

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