Literature DB >> 15281326

The relationship between asthma and obesity in children: is it real or a case of over diagnosis?

Haim Bibi1, David Shoseyov, David Feigenbaum, Marina Genis, Michael Friger, Ronit Peled, Shimon Sharff.   

Abstract

OBJECTIVE: To determine whether obesity among children is associated with an increased incidence of asthma. DESIGN AND
METHOD: Five thousand nine hundred eighty-four children participated in a lung health study in the Ashkelon region, Israel. A lung health questionnaire was completed and they underwent spirometry. Body mass index (BMI) was then calculated for each child.
RESULTS: Three hundred two children (5.05%) were above the 95th percentile for BMI and considered obese. Obese children tended to wheeze more than the non-obese children 14.5% vs. 10.5%, respectively (p<0.038). Asthma (physician diagnosis) was diagnosed more often among obese children than non-obese 7.2% vs. 3.9%, respectively (p<0.008). Inhaler use was more prevalent among obese children than non-obese 15.9% vs. 8.8%, respectively (p<0.001). Bronchial hyperreactivity was significantly greater among the non-obese asthmatic children compared with their obese counterparts, 352 (51.4%) vs. 10 (27.8%), respectively (p<0.001). Chest symptoms and asthma were more frequent in obese than non-obese boys.
CONCLUSION: Asthma, wheezing, and inhaler use were more common in obese children than in non-obese children. Symptoms were more prevalent among obese boys. Increasing BMI among children is a risk factor for asthma, which may in reality be obesity-related chest symptoms that mimic asthma.

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Year:  2004        PMID: 15281326     DOI: 10.1081/jas-120026097

Source DB:  PubMed          Journal:  J Asthma        ISSN: 0277-0903            Impact factor:   2.515


  34 in total

1.  Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype.

Authors:  Njira L Lugogo; John W Hollingsworth; Druhan L Howell; Loretta G Que; Dave Francisco; Tony D Church; Erin N Potts-Kant; Jennifer L Ingram; Ying Wang; Sin-Ho Jung; Monica Kraft
Journal:  Am J Respir Crit Care Med       Date:  2012-07-05       Impact factor: 21.405

2.  Atopic disease and cardiovascular risk factors in US children.

Authors:  Jonathan I Silverberg
Journal:  J Allergy Clin Immunol       Date:  2015-12-08       Impact factor: 10.793

3.  Relationship between asthma, overweight, and physical activity among U.S. high school students.

Authors:  Sherry Everett Jones; Sarah L Merkle; Janet E Fulton; Lani S Wheeler; David M Mannino
Journal:  J Community Health       Date:  2006-12

4.  Family mealtime interactions and overweight children with asthma: potential for compounded risks?

Authors:  Matthew P Jacobs; Barbara H Fiese
Journal:  J Pediatr Psychol       Date:  2006-09-01

5.  Physical activity, restrictions in activity, and body mass index among urban children with persistent asthma.

Authors:  Heather Holderness; Nancy Chin; Deborah J Ossip; Maria Fagnano; Marina Reznik; Jill S Halterman
Journal:  Ann Allergy Asthma Immunol       Date:  2017-03-06       Impact factor: 6.347

Review 6.  Obesity and asthma.

Authors:  David A Beuther; Scott T Weiss; E Rand Sutherland
Journal:  Am J Respir Crit Care Med       Date:  2006-04-20       Impact factor: 21.405

7.  Percent body fat, skinfold thickness or body mass index for defining obesity or overweight, as a risk factor for asthma in schoolchildren: which one to use in epidemiological studies?

Authors:  Luis Garcia-Marcos; Jose Valverde-Molina; Maria L Castaños Ortega; Manuel Sanchez-Solis; Antonia E Martinez-Torres; Jose A Castro-Rodríguez
Journal:  Matern Child Nutr       Date:  2008-10       Impact factor: 3.092

8.  Gender differences in the association of overweight and asthma morbidity among urban adolescents with asthma.

Authors:  C L M Joseph; S L Havstad; D R Ownby; E Zoratti; E L Peterson; S Stringer; C C Johnson
Journal:  Pediatr Allergy Immunol       Date:  2008-09-22       Impact factor: 6.377

9.  Asthma symptom perception and obesity in children.

Authors:  Sheryl J Kopel; Natalie Walders-Abramson; Elizabeth L McQuaid; Ronald Seifer; Daphne Koinis-Mitchell; Robert B Klein; Marianne Z Wamboldt; Gregory K Fritz
Journal:  Biol Psychol       Date:  2009-11-24       Impact factor: 3.251

10.  Frequency and correlates of overweight status in adolescent asthma.

Authors:  Natalie Walders Abramson; Frederick S Wamboldt; Anthony L Mansell; Rick Carter; Monica J Federico; Marianne Z Wamboldt
Journal:  J Asthma       Date:  2008-03       Impact factor: 2.515

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