Literature DB >> 15281275

Identification of major active constituents in the fingerprint of Salvia miltiorrhiza Bunge developed by high-speed counter-current chromatography.

Ming Gu1, Guifeng Zhang, Zhiguo Su, Fan Ouyang.   

Abstract

High-speed counter-current chromatography was applied as a method to develop fingerprinting of Salvia miltiorrhiza Bunge, a popular traditional Chinese medicine, in our previous study. Important active constituents that were directly related to the therapy effect should be identified. Each effluent fraction and standard samples (cryptotanshinone, tanshinoneI and tanshinoneIIA) were analyzed by ultraviolet spectroscopy and liquid chromatography-mass spectroscopy. It was concluded from the UV-Vis spectrograms, retention times in LC analysis and mass spectrograms, that fractions 7, 8 and 11 were respectively cryptotanshinone (Mr 296), tanshinone I (Mr 276) and tanshinone IIA (Mr 294).

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Year:  2004        PMID： 15281275     DOI： 10.1016/j.chroma.2004.04.030

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN： 0021-9673            Impact factor:   4.759


  14 in total

1.  Inhibitory effect of salvianolate on human cytochrome P450 3A4 in vitro involving a noncompetitive manner.

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Journal:  Int J Clin Exp Med       Date:  2015-09-15

Review 2.  Combating Drug Resistance in Colorectal Cancer Using Herbal Medicines.

Authors:  Ga-Young Lee; Jin-Seok Lee; Chang-Gue Son; Nam-Hun Lee
Journal:  Chin J Integr Med       Date:  2020-08-01       Impact factor: 1.978

3.  HLA-A*02:01 allele is associated with tanshinone-induced cutaneous drug reactions in Chinese population.

Authors:  Qinyuan Zhu; Yanzhou Zhang; Jiekun Xuan; Fanping Yang; Binbin Du; Sheng-An Chen; Sijia Yan; Menglin Jiang; Huizhong Zhu; Hao Xiong; Xiaoqun Luo; Qinghe Xing
Journal:  Pharmacogenomics J       Date:  2019-12-03       Impact factor: 3.550

4.  Neuroprotective effects of tanshinone I from Danshen extract in a mouse model of hypoxia-ischemia.

Authors:  Jae-Chul Lee; Joon Ha Park; Ok Kyu Park; In Hye Kim; Bing Chun Yan; Ji Hyeon Ahn; Seung-Hae Kwon; Jung Hoon Choi; Jong-Dai Kim; Moo-Ho Won
Journal:  Anat Cell Biol       Date:  2013-09-30

5.  Synergistic Effect between Cryptotanshinone and Antibiotics against Clinic Methicillin and Vancomycin-Resistant Staphylococcus aureus.

Authors:  Jeong-Dan Cha; Jeong-Ho Lee; Kyung Min Choi; Sung-Mi Choi; Jeong Hye Park
Journal:  Evid Based Complement Alternat Med       Date:  2014-03-24       Impact factor: 2.629

6.  Activation of ER Stress-Dependent miR-216b Has a Critical Role in Salviamiltiorrhiza Ethanol-Extract-Induced Apoptosis in U266 and U937 Cells.

Authors:  Changmin Kim; Hyo-Sook Song; Hojung Park; Bonglee Kim
Journal:  Int J Mol Sci       Date:  2018-04-19       Impact factor: 5.923

7.  Tanshinone IIA attenuates nerve structural and functional damage induced by nerve crush injury in rats.

Authors:  Zhiyong Wang; Xiaomei Yang; Weiguang Zhang; Peixun Zhang; Baoguo Jiang
Journal:  PLoS One       Date:  2018-08-23       Impact factor: 3.240

Review 8.  Tanshinones: sources, pharmacokinetics and anti-cancer activities.

Authors:  Yong Zhang; Peixin Jiang; Min Ye; Sung-Hoon Kim; Cheng Jiang; Junxuan Lü
Journal:  Int J Mol Sci       Date:  2012-10-22       Impact factor: 5.923

9.  Apoptosis Induced by Tanshinone IIA and Cryptotanshinone Is Mediated by Distinct JAK/STAT3/5 and SHP1/2 Signaling in Chronic Myeloid Leukemia K562 Cells.

Authors:  Ji Hoon Jung; Tae-Rin Kwon; Soo-Jin Jeong; Eun-Ok Kim; Eun Jung Sohn; Miyong Yun; Sung-Hoon Kim
Journal:  Evid Based Complement Alternat Med       Date:  2013-06-26       Impact factor: 2.629

Review 10.  Counter-current chromatography for the separation of terpenoids: a comprehensive review with respect to the solvent systems employed.

Authors:  Krystyna Skalicka-Woźniak; Ian Garrard
Journal:  Phytochem Rev       Date:  2014-03-25       Impact factor: 5.374
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