| Literature DB >> 15280961 |
Yusuke Imamura1, Hirosato Takikawa, Mitsuru Sasaki, Kenji Mori.
Abstract
The first synthesis of mispyric acid (1), an inhibitor of DNA polymerase beta with a novel triterpene skeleton, was achieved by starting from isoprene (2), geraniol (6) and 1,5-dimethoxy-1,4-cyclohexadiene (14). The absolute configuration of the naturally occurring 1 was determined as 2S,4S.Entities:
Year: 2004 PMID： 15280961 DOI： 10.1039/b406820c
Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876