Literature DB >> 1527989

Azelaic and pimelic acids: metabolic intermediates or artefacts?

M J Bennett1, M C Ragni, I Hood, D E Hale.   

Abstract

Azelaic and pimelic acids are excreted in elevated amounts in urine in disorders of mitochondrial beta-oxidation and disorders of peroxisomal beta-oxidation, for which they are of significant diagnostic value. We have detected the presence of azelaic, pimelic and even-chain-length dicarboxylic acids (adipic, suberic and sebacic acids) arising artefactually as a result of storage of small sample volumes in plastic containers. Storage of samples for organic acid analysis in glass containers is recommended.

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Year:  1992        PMID： 1527989     DOI： 10.1007/bf01799635

Source DB:  PubMed          Journal:  J Inherit Metab Dis        ISSN： 0141-8955            Impact factor:   4.982


  5 in total

1.  Retrospective diagnosis of 3-hydroxydicarboxylic aciduria by analysis of filter paper blood samples.

Authors:  U von Döbeln; N Venizelos; L Hagenfeldt
Journal:  J Inherit Metab Dis       Date:  1990       Impact factor: 4.982

2.  General (medium-chain) acyl-CoA dehydrogenase deficiency (non-ketotic dicarboxylic aciduria): quantitative urinary excretion pattern of 23 biologically significant organic acids in three cases.

Authors:  N Gregersen; S Kølvraa; K Rasmussen; P B Mortensen; P Divry; M David; N Hobolth
Journal:  Clin Chim Acta       Date:  1983-08-15       Impact factor: 3.786

3.  The routine investigation of urinary organic acids in selected paediatric patients: results over a 2 1/2-year period.

Authors:  M J Bennett; A Green; R J Pollitt; E Worthy
Journal:  Ann Clin Biochem       Date:  1984-01       Impact factor: 2.057

4.  Medium- and long-chain dicarboxylic aciduria in patients with Zellweger syndrome and neonatal adrenoleukodystrophy.

Authors:  F Rocchiccioli; P Aubourg; P F Bougnères
Journal:  Pediatr Res       Date:  1986-01       Impact factor: 3.756

5.  Episodic hypoglycemia with psi-hydroxy fatty acid excretion.

Authors:  E Colle; O A Mamer; J A Montgomery; J D Miller
Journal:  Pediatr Res       Date:  1983-02       Impact factor: 3.756
  5 in total
  3 in total

1.  Characteristic urine organic acid profile in peroxisomal biogenesis disorders.

Authors:  S H Korman; H Mandel; A Gutman
Journal:  J Inherit Metab Dis       Date:  2000-06       Impact factor: 4.982

2.  Evaluation of a gas chromatography method for azelaic acid determination in selected biological samples.

Authors:  Mahdi Garelnabi; Dmitry Litvinov; Sampath Parthasarathy
Journal:  N Am J Med Sci       Date:  2010-09

Review 3.  Bioinformatics: the next frontier of metabolomics.

Authors:  Caroline H Johnson; Julijana Ivanisevic; H Paul Benton; Gary Siuzdak
Journal:  Anal Chem       Date:  2014-11-20       Impact factor: 6.986
  3 in total

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