Literature DB >> 15279818

Management of other complications specific to monochorionic twin pregnancies.

L Pasquini1, R C Wimalasundera, N M Fisk.   

Abstract

Monochorionic (MC) twins have a 3-10-fold higher perinatal mortality and morbidity than dichorionic twins. This is largely attributable to their common vascular architecture and the high rate of discordant fetal growth, growth restriction and congenital abnormalities. In the event of a single intrauterine death (IUD), intertwin agonal transfusion results in up to a 38% risk of death and a 46% risk of neurological injury to the co-twin. This chapter addresses the management of complications unique to MC twins. The primary aim of management is to prevent single IUD or, if inevitable, prevent agonal transfusion occurring by vascular occlusive selective feticide. Older fetoscopic techniques have been replaced by the simpler ultrasound-guided techniques of interstitial laser and bipolar cord occlusion. Their application in twin reversed-arterial perfusion sequence has been associated with a 50% reduction of perinatal mortality in the pump twin. Moreover, prophylactic interstitial laser therapy in early pregnancy might obviate the technical and clinical difficulties in the presence of fetal decompensation in later pregnancy. Recent strategies to reduce the high perinatal mortality due to cord entanglement in antenatally diagnosed monoamniotic twins including medical amnioreduction and elective caesarean delivery at 32 weeks, are also discussed.

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Year:  2004        PMID: 15279818     DOI: 10.1016/j.bpobgyn.2004.04.011

Source DB:  PubMed          Journal:  Best Pract Res Clin Obstet Gynaecol        ISSN: 1521-6934            Impact factor:   5.237


  3 in total

1.  Rapid initiation of fetal therapy services with a system of learner-centred training under proctorship: the National University Hospital (Singapore) experience.

Authors:  Arundhati Gosavi; Pradip D Vijayakumar; Bryan Sw Ng; May-Han Loh; Lay Geok Tan; Nuryanti Johana; Yi Wan Tan; Dedy Sandikin; Lin Lin Su; Tuangsit Wataganara; Arijit Biswas; Mahesh A Choolani; Citra Nz Mattar
Journal:  Singapore Med J       Date:  2016-07-21       Impact factor: 1.858

2.  Monoamniotic twins with one fetal anencephaly and cord entanglement diagnosed with three dimensional ultrasound at 14 weeks of gestation.

Authors:  Yun Sung Jo; Hyun Joo Son; Dong Gyu Jang; Narinay Kim; Guisera Lee
Journal:  Int J Med Sci       Date:  2011-09-29       Impact factor: 3.738

3.  High risk of unexpected late fetal death in monochorionic twins despite intensive ultrasound surveillance: a cohort study.

Authors:  Olivia Barigye; Lucia Pasquini; Paula Galea; Helen Chambers; Lucy Chappell; Nicholas M Fisk
Journal:  PLoS Med       Date:  2005-06-28       Impact factor: 11.069

  3 in total

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