Literature DB >> 15278196

[Preclinical management of accidental methadone intoxication of a 4-year-old girl. Antagonist or intubation?].

C Hainer1, M Bernhard, A Gries.   

Abstract

We report on the preclinical management of a 4-year-old child who was found in a comatose condition with respiratory failure after accidental ingestion of methadone. Emergency airway management was carried out with endotracheal intubation instead of administering the antagonist naloxone. The child could be extubated 12 h later and was released from hospital after 3 days with no neurological symptoms. The authors attempt to formulate an algorithm for the preclinical management of opioid intoxication with reference to the literature and own experience. Endotracheal intubation seems to be superior to the use of the antagonist naloxone, especially in a critical situation. This is the only way to ensure a rapid oxygenation with adequate airway protection and with the simultaneous avoidance of the side-effects of naloxone. A restrictive and critical administration of the opioid antagonist naloxone is recommended when there is suspicion of opioid ingestion but no signs of intoxication.

Entities:  

Mesh:

Substances:

Year:  2004        PMID: 15278196     DOI: 10.1007/s00101-004-0730-0

Source DB:  PubMed          Journal:  Anaesthesist        ISSN: 0003-2417            Impact factor:   1.041


  11 in total

Review 1.  [Drug substitution in heroin dependence with methadone].

Authors:  M Krausz; P Raschke; D Naber
Journal:  Internist (Berl)       Date:  1999-06       Impact factor: 0.743

2.  Naloxone--for intoxications with intravenous heroin and heroin mixtures--harmless or hazardous? A prospective clinical study.

Authors:  J J Osterwalder
Journal:  J Toxicol Clin Toxicol       Date:  1996

3.  Two cases of naloxone-induced pulmonary oedema--the possible use of phentolamine in management.

Authors:  J Brimacombe; J Archdeacon; S Newell; J Martin
Journal:  Anaesth Intensive Care       Date:  1991-11       Impact factor: 1.669

4.  Survey of out-of-hospital emergency intubations in the French prehospital medical system: a multicenter study.

Authors:  F Adnet; N J Jouriles; P Le Toumelin; B Hennequin; C Taillandier; F Rayeh; J Couvreur; B Nougière; P Nadiras; A Ladka; M Fleury
Journal:  Ann Emerg Med       Date:  1998-10       Impact factor: 5.721

5.  An apparent epidemic: methadone poisoning in children.

Authors:  R Aronow; S L Brenner; P V Woolley
Journal:  Clin Toxicol       Date:  1973       Impact factor: 4.467

6.  A prospective study of tracheal intubation in an emergency department in Hong Kong.

Authors:  A Y Tam; F L Lau
Journal:  Eur J Emerg Med       Date:  2001-12       Impact factor: 2.799

7.  Airway management in the emergency department: a one-year study of 610 tracheal intubations.

Authors:  J C Sakles; E G Laurin; A A Rantapaa; E A Panacek
Journal:  Ann Emerg Med       Date:  1998-03       Impact factor: 5.721

8.  Prehospital endotracheal intubation of children by paramedics.

Authors:  D Brownstein; R Shugerman; P Cummings; F Rivara; M Copass
Journal:  Ann Emerg Med       Date:  1996-07       Impact factor: 5.721

9.  Emergency intubation of the pediatric medical patient: use of anesthetic agents in the emergency department.

Authors:  K Gnauck; J B Lungo; A Scalzo; J Peter; A Nakanishi
Journal:  Ann Emerg Med       Date:  1994-06       Impact factor: 5.721

10.  Naloxone-induced pulmonary edema.

Authors:  J A Schwartz; M D Koenigsberg
Journal:  Ann Emerg Med       Date:  1987-11       Impact factor: 5.721

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.