Literature DB >> 15278156

Lipase catalysed Michael addition of secondary amines to acrylonitrile.

Oliver Torre1, Ignacio Alfonso, Vicente Gotor.   

Abstract

A new enzymatic process is described. Different preparations of lipase B from Candida antarctica are able to catalyse Michael-type addition of secondary amines to acrylonitrile. This new reaction widens the applicability of these biocatalysts in organic synthesis.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15278156     DOI： 10.1039/b402244k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  Computational design of a lipase for catalysis of the Diels-Alder reaction.

Authors:  Mats Linder; Anders Hermansson; John Liebeschuetz; Tore Brinck
Journal:  J Mol Model       Date:  2010-06-24       Impact factor: 1.810

2.  How the Same Core Catalytic Machinery Catalyzes 17 Different Reactions: the Serine-Histidine-Aspartate Catalytic Triad of α/β-Hydrolase Fold Enzymes.

Authors:  Alissa Rauwerdink; Romas J Kazlauskas
Journal:  ACS Catal       Date:  2015-09-09       Impact factor: 13.084

Review 3.  Stereoselective Promiscuous Reactions Catalyzed by Lipases.

Authors:  Angela Patti; Claudia Sanfilippo
Journal:  Int J Mol Sci       Date:  2022-02-28       Impact factor: 5.923

4.  Promiscuous Lipase-Catalyzed Markovnikov Addition of H-Phosphites to Vinyl Esters for the Synthesis of Cytotoxic α-Acyloxy Phosphonate Derivatives.

Authors:  Paweł Kowalczyk; Dominik Koszelewski; Barbara Gawdzik; Jan Samsonowicz-Górski; Karol Kramkowski; Aleksandra Wypych; Rafał Lizut; Ryszard Ostaszewski
Journal:  Materials (Basel)       Date:  2022-03-07       Impact factor: 3.623

5.  Biocatalytic decarboxylative Michael addition for synthesis of 1,4-benzoxazinone derivatives.

Authors:  Hossein Bavandi; Mansour Shahedi; Zohreh Habibi; Maryam Yousefi; Jesper Brask; Mehdi Mohammadi
Journal:  Sci Rep       Date:  2022-07-26       Impact factor: 4.996

6.  Promiscuous Lipase-Catalyzed Knoevenagel-Phospha-Michael Reaction for the Synthesis of Antimicrobial β-Phosphono Malonates.

Authors:  Jan Samsonowicz-Górski; Dominik Koszelewski; Paweł Kowalczyk; Paweł Śmigielski; Anastasiia Hrunyk; Karol Kramkowski; Aleksandra Wypych; Mateusz Szymczak; Rafał Lizut; Ryszard Ostaszewski
Journal:  Int J Mol Sci       Date:  2022-08-08       Impact factor: 6.208

7.  Efficient asymmetric synthesis of 1-cyano-tetrahydroisoquinolines from lipase dual activity and opposite enantioselectivities in α-Aminonitrile resolution.

Authors:  Morakot Sakulsombat; Pornrapee Vongvilai; Olof Ramström
Journal:  Chemistry       Date:  2014-07-23       Impact factor: 5.236

8.  Uses of 2-ethoxy-4(3H) quinazolinone in synthesis of quinazoline and quinazolinone derivatives of antimicrobial activity: the solvent effect.

Authors:  Maher A El-Hashash; Sameh A Rizk; Khalid M Darwish; Fakhry A El-Bassiouny
Journal:  Glob J Health Sci       Date:  2011-12-29
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.