Literature DB >> 15278008

Topical honey application vs. acyclovir for the treatment of recurrent herpes simplex lesions.

Noori S Al-Waili1.   

Abstract

BACKGROUND: The objective of this research was to investigate the effect of the topical application of honey on recurrent attacks of herpes lesions, labial and genital, as compared to acyclovir cream. MATERIAL/
METHODS: Sixteen adult patients with a history of recurrent attacks of herpetic lesions, 8 labial and 8 genital, were treated by topical application of honey for one attack and acyclovir cream for another attack.
RESULTS: For labial herpes, the mean duration of attacks and pain, occurrence of crusting, and mean healing time with honey treatment were 35%, 39%, 28% and 43% better, respectively, than with acyclovir treatment. For genital herpes, the mean duration of attacks and pain, occurrence of crusting, and mean healing time with honey treatment were 53%, 50%, 49% and 59% better, respectively, than with acyclovir. Two cases of labial herpes and one case of genital herpes remitted completely with the use of honey. The lesions crusted in 3 patients with labial herpes and in 4 patients with genital herpes. With acyclovir treatment, none of the attacks remitted, and all the lesions, labial and genital, developed crust. No side effects were observed with repeated applications of honey, whereas 3 patients developed local itching with acyclovir.
CONCLUSIONS: Topical honey application is safe and effective in the management of the signs and symptoms of recurrent lesions from labial and genital herpes.

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Year:  2004        PMID: 15278008

Source DB:  PubMed          Journal:  Med Sci Monit        ISSN: 1234-1010


  24 in total

1.  Effect of honey on bacterial translocation and intestinal morphology in obstructive jaundice.

Authors:  Cem Gencay; Sibel-Serin Kilicoglu; Kemal Kismet; Bulent Kilicoglu; Serap Erel; Sabahattin Muratoglu; Asli-Elif Sunay; Esra Erdemli; Mehmet-Ali Akkus
Journal:  World J Gastroenterol       Date:  2008-06-07       Impact factor: 5.742

2.  In vitro antiviral activity of honey against varicella zoster virus (VZV): A translational medicine study for potential remedy for shingles.

Authors:  Aamir Shahzad; Randall J Cohrs
Journal:  Transl Biomed       Date:  2012

3.  Physico-chemical analysis and antimicrobial potential of Apis dorsata, Apis mellifera and Ziziphus jujube honey samples from Pakistan.

Authors:  Hira Fahim; Javid Iqbal Dasti; Ihsan Ali; Safia Ahmed; Muhammad Nadeem
Journal:  Asian Pac J Trop Biomed       Date:  2014-08

4.  A Randomized Phase 2 Trial of Prophylactic Manuka Honey for the Reduction of Chemoradiation Therapy-Induced Esophagitis During the Treatment of Lung Cancer: Results of NRG Oncology RTOG 1012.

Authors:  Shannon E Fogh; Snehal Deshmukh; Lawrence B Berk; Amylou C Dueck; Kevin Roof; Sherif Yacoub; Thomas Gergel; Kevin Stephans; Andreas Rimner; Albert DeNittis; John Pablo; Justin Rineer; Terence M Williams; Deborah Bruner
Journal:  Int J Radiat Oncol Biol Phys       Date:  2016-11-23       Impact factor: 7.038

Review 5.  Wound care with antibacterial honey (Medihoney) in pediatric hematology-oncology.

Authors:  Arne Simon; Kai Sofka; Gertrud Wiszniewsky; Gisela Blaser; Udo Bode; Gudrun Fleischhack
Journal:  Support Care Cancer       Date:  2005-08-02       Impact factor: 3.603

6.  Honey and cancer: sustainable inverse relationship particularly for developing nations-a review.

Authors:  Nor Hayati Othman
Journal:  Evid Based Complement Alternat Med       Date:  2012-06-17       Impact factor: 2.629

Review 7.  Does honey have the characteristics of natural cancer vaccine?

Authors:  Nor Hayati Othman
Journal:  J Tradit Complement Med       Date:  2012-10

8.  Medical honey for wound care--still the 'latest resort'?

Authors:  Arne Simon; Kirsten Traynor; Kai Santos; Gisela Blaser; Udo Bode; Peter Molan
Journal:  Evid Based Complement Alternat Med       Date:  2008-01-07       Impact factor: 2.629

9.  Honey - a potential agent against Porphyromonas gingivalis: an in vitro study.

Authors:  Sigrun Eick; Gesine Schäfer; Jakub Kwieciński; Julia Atrott; Thomas Henle; Wolfgang Pfister
Journal:  BMC Oral Health       Date:  2014-03-25       Impact factor: 2.757

10.  Efficacy of topical alpha ointment (containing natural henna) compared to topical hydrocortisone (1%) in the healing of radiation-induced dermatitis in patients with breast cancer: a randomized controlled clinical trial.

Authors:  Mansour Ansari; Dehsara Farzin; Ahmad Mosalaei; Shapour Omidvari; Niloofar Ahmadloo; Mohammad Mohammadianpanah
Journal:  Iran J Med Sci       Date:  2013-12
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