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Literature DB >> 15277768

8-Hydroxydaidzein, an aldose reductase inhibitor from okara fermented with Aspergillus sp. HK-388.

Tomoyuki Fujita¹, Tomoyoshi Funako, Hideo Hayashi.

Abstract

The aldose reductase (AR) inhibitor, 8-hydroxydaidzein, was isolated and identified from a methanolic extract of okara (soybean pulp) fermented with the fungal strain, Aspergillus sp. HK-388. 8-Hydroxydaidzein showed non-competitive inhibition of human recombinant AR with respect to DL-glyceraldehyde, its Ki value being evaluated as 7.0 microM.

Entities: Chemical Species

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Year: 2004 PMID： 15277768 DOI： 10.1271/bbb.68.1588

Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN： 0916-8451 Impact factor: 2.043

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Cited

8 in total

1. Microbial transformation of bioactive compounds and production of ortho-dihydroxyisoflavones and glycitein from natural fermented soybean paste.

Authors: Changhyun Roh
Journal: Biomolecules Date: 2014-12-12

2. In vitro antidiabetic effects of selected fruits and vegetables against glycosidase and aldose reductase.

Authors: Tong Wu; Jiaqiang Luo; Baojun Xu
Journal: Food Sci Nutr Date: 2015-04-30 Impact factor: 2.863

3. Production of Two Novel Methoxy-Isoflavones from Biotransformation of 8-Hydroxydaidzein by Recombinant Escherichia coli Expressing O-Methyltransferase SpOMT2884 from Streptomyces peucetius.

Authors: Chien-Min Chiang; Hsiou-Yu Ding; Ya-Ting Tsai; Te-Sheng Chang
Journal: Int J Mol Sci Date: 2015-11-24 Impact factor: 5.923

Review 4. Isolation, bioactivity, and production of ortho-hydroxydaidzein and ortho-hydroxygenistein.

Authors: Te-Sheng Chang
Journal: Int J Mol Sci Date: 2014-04-03 Impact factor: 5.923

5. The Antioxidant and Anti-Inflammatory Activities of 8-Hydroxydaidzein (8-HD) in Activated Macrophage-Like RAW264.7 Cells.

Authors: Eunji Kim; Young-Gyu Kang; Ji Hye Kim; Yong-Jin Kim; Tae Ryong Lee; Jongsung Lee; Donghyun Kim; Jae Youl Cho
Journal: Int J Mol Sci Date: 2018-06-21 Impact factor: 5.923

8-Hydroxydaidzein, an aldose reductase inhibitor from okara fermented with Aspergillus sp. HK-388.

1. Microbial transformation of bioactive compounds and production of ortho-dihydroxyisoflavones and glycitein from natural fermented soybean paste.

2. In vitro antidiabetic effects of selected fruits and vegetables against glycosidase and aldose reductase.

3. Production of Two Novel Methoxy-Isoflavones from Biotransformation of 8-Hydroxydaidzein by Recombinant Escherichia coli Expressing O-Methyltransferase SpOMT2884 from Streptomyces peucetius.

Review 4. Isolation, bioactivity, and production of ortho-hydroxydaidzein and ortho-hydroxygenistein.

5. The Antioxidant and Anti-Inflammatory Activities of 8-Hydroxydaidzein (8-HD) in Activated Macrophage-Like RAW264.7 Cells.

Review 6. Valorisation of By-Products from Soybean (Glycine max (L.) Merr.) Processing.

Review 7. Naturally Occurring Flavonoids and Isoflavonoids and Their Microbial Transformation: A Review.

8. 8-Hydroxydaidzein Downregulates JAK/STAT, MMP, Oxidative Phosphorylation, and PI3K/AKT Pathways in K562 Cells.