Literature DB >> 15275441

Leishmania infantum tropism: strain genotype or host immune status?

L Gradoni1, M Gramiccia.   

Abstract

In apparently immunocompetent patients, Leishmania infantum provokes a spectrum of disease, ranging from simple skin lesion to severe visceral leishmaniasis, that is determined mainly by the protozoan genotype. In HIV-positive individuals, leishmanial infection results almost exclusively in visceral disease. In this review, Luigi Grodoni and Marina Gromiccia discuss the role o f the intrinsic virulence of L. infantum strains and the immune condition of the host, and focus on recently described mechanisms of immunological control of leishmanial infection.

Entities:  

Year:  1994        PMID： 15275441     DOI： 10.1016/0169-4758(94)90142-2

Source DB:  PubMed          Journal:  Parasitol Today        ISSN： 0169-4758


  21 in total

1.  Leishmania infection impairs beta 1-integrin function and chemokine receptor expression in mononuclear phagocytes.

Authors:  Nathanael F Pinheiro; Micely D R Hermida; Mariana P Macedo; José Mengel; Andre Bafica; Washington L C dos-Santos
Journal:  Infect Immun       Date:  2006-07       Impact factor: 3.441

Review 2.  Leishmania and human immunodeficiency virus coinfection: the first 10 years.

Authors:  J Alvar; C Cañavate; B Gutiérrez-Solar; M Jiménez; F Laguna; R López-Vélez; R Molina; J Moreno
Journal:  Clin Microbiol Rev       Date:  1997-04       Impact factor: 26.132

3.  Molecular characterization of Leishamania isolates from China by inter-simple sequence repeat polymerase chain reaction.

Authors:  Yong Wang; Yuetao Yang; Junyun Wang; Yifang Bao; Liren Guan; Chunhua Gao; Feng Shi
Journal:  Parasitol Res       Date:  2010-03-17       Impact factor: 2.289

4.  Virulence of Leishmania infantum is expressed as a clonal and dominant phenotype in experimental infections.

Authors:  Y J Garin; A Sulahian; F Pratlong; P Meneceur; J P Gangneux; E Prina; J P Dedet; F Derouin
Journal:  Infect Immun       Date:  2001-12       Impact factor: 3.441

5.  Molecular Analysis of A2-genes Encoding Stage-specific S Antigen-like Proteins among Isolates from Iranian Cutaneous and Visceral Leishmaniasis.

Authors:  Mahin Farahmand; Hasti Atashi Shirazi; Hossein Nahrevanian; Homa Hajjaran
Journal:  Iran J Basic Med Sci       Date:  2011-09       Impact factor: 2.699

6.  Effects of tropism and virulence of Leishmania parasites on cytokine production by infected human monocytes.

Authors:  A Meddeb-Garnaoui; H Zrelli; K Dellagi
Journal:  Clin Exp Immunol       Date:  2008-11-20       Impact factor: 4.330

7.  Effect of chlorpyrifos on healing of cutaneous leishmaniasis lesions after treatment with Pentostam(®).

Authors:  Asya N Al-Dawood; Ramadan A Al-Ghazal; May H Al-Jaser; Galila M Khalil
Journal:  Saudi J Biol Sci       Date:  2009-07       Impact factor: 4.219

8.  CD4+ CCR5+ and CD4+ CCR3+ lymphocyte subset and monocyte apoptosis in patients with acute visceral leishmaniasis.

Authors:  Marcella Potestio; Pietro D'Agostino; Giuseppina Colonna Romano; Salvatore Milano; Viviana Ferlazzo; Alessandra Aquino; Gloria Di Bella; Rosalba Caruso; Giuseppe Gambino; Giustina Vitale; Serafino Mansueto; Enrico Cillari
Journal:  Immunology       Date:  2004-10       Impact factor: 7.397

9.  Virulence attenuation of a UDP-galactose/N-acetylglucosamine beta1,4 galactosyltransferase expressing Leishmania donovani promastigote.

Authors:  S K Bhaumik; M Singh; R Basu; S Bhaumik; K Roychoudhury; K Naskar; S Roy; T De
Journal:  Glycoconj J       Date:  2008-01-16       Impact factor: 2.916

10.  FIRST REPORT OF CUTANEOUS LEISHMANIASIS CAUSED BY Leishmania (Leishmania) infantum chagasi IN AN URBAN AREA OF RIO DE JANEIRO, BRAZIL.

Authors:  Marcelo Rosandiski Lyra; Maria Inês Fernandes Pimentel; Maria de Fátima Madeira; Liliane de Fátima Antonio; Janine Pontes de Miranda Lyra; Aline Fagundes; Armando de Oliveira Schubach
Journal:  Rev Inst Med Trop Sao Paulo       Date:  2015 Sep-Oct       Impact factor: 1.846
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