Literature DB >> 15275335

Mefloquine resistance in Plasmodium falciparum.

F P Mockenhaupt1.   

Abstract

Mefloquine resistance in Plasmodium falciparum, the most dangerous of the four pathogenic malaria parasites of humans, is established in several endemic regions of the world. After a promising start, resistance has developed to disturbing extents in some areas, whereas in many regions it remains an effective drug. In this article, Frank Mockenhaupt reviews the factors that are likely to influence the development of mefloquine resistance, its possible mechanism and its geographical spread.

Entities:  

Year:  1995        PMID： 15275335     DOI： 10.1016/0169-4758(95)80201-0

Source DB:  PubMed          Journal:  Parasitol Today        ISSN： 0169-4758


  13 in total

1.  In vitro sensitivity of Plasmodium falciparum clinical isolates from the China-Myanmar border area to quinine and association with polymorphism in the Na+/H+ exchanger.

Authors:  Hao Meng; Rongping Zhang; Henglin Yang; Qi Fan; Xinzhuan Su; Jun Miao; Liwang Cui; Zhaoqing Yang
Journal:  Antimicrob Agents Chemother       Date:  2010-07-19       Impact factor: 5.191

2.  [Malaria--current diagnosis and therapy].

Authors:  Isabel Barreto Miranda; Thomas Löscher
Journal:  Med Klin (Munich)       Date:  2009-07-15

3.  Comparative molecular field analysis of artemisinin derivatives: ab initio versus semiempirical optimized structures.

Authors:  S Tonmunphean; S Kokpol; V Parasuk; P Wolschann; R H Winger; K R Liedl; B M Rode
Journal:  J Comput Aided Mol Des       Date:  1998-07       Impact factor: 3.686

4.  Mechanisms of in vitro resistance to dihydroartemisinin in Plasmodium falciparum.

Authors:  Long Cui; Zenglei Wang; Jun Miao; Miao Miao; Ramesh Chandra; Hongying Jiang; Xin-zhuan Su; Liwang Cui
Journal:  Mol Microbiol       Date:  2012-08-06       Impact factor: 3.501

5.  pfmdr1 amplification and fixation of pfcrt chloroquine resistance alleles in Plasmodium falciparum in Venezuela.

Authors:  Sean Griffing; Luke Syphard; Sankar Sridaran; Andrea M McCollum; Tonya Mixson-Hayden; Sumiti Vinayak; Leopoldo Villegas; John W Barnwell; Ananias A Escalante; Venkatachalam Udhayakumar
Journal:  Antimicrob Agents Chemother       Date:  2010-02-09       Impact factor: 5.191

Review 6.  Drug interactions in the treatment and chemoprophylaxis of malaria in HIV infected individuals in sub Saharan Africa.

Authors:  Fatai A Fehintola; Olusegun O Akinyinka; Isaac F Adewole; Chiedza C Maponga; Qing Ma; Gene D Morse
Journal:  Curr Drug Metab       Date:  2011-01       Impact factor: 3.731

7.  Inhibitory effects of pepstatin A and mefloquine on the growth of Babesia parasites.

Authors:  Tserendorj Munkhjargal; Mahmoud AbouLaila; Mohamad Alaa Terkawi; Thillaiampalam Sivakumar; Madoka Ichikawa; Batdorj Davaasuren; Tserendorj Nyamjargal; Naoaki Yokoyama; Ikuo Igarashi
Journal:  Am J Trop Med Hyg       Date:  2012-08-13       Impact factor: 2.345

Review 8.  Antimalarial drug toxicity: a review.

Authors:  W Robert J Taylor; Nicholas J White
Journal:  Drug Saf       Date:  2004       Impact factor: 5.606

Review 9.  Artesunate. A review of its pharmacology and therapeutic efficacy in the treatment of malaria.

Authors:  L B Barradell; A Fitton
Journal:  Drugs       Date:  1995-10       Impact factor: 9.546

Review 10.  Discovery, mechanisms of action and combination therapy of artemisinin.

Authors:  Liwang Cui; Xin-zhuan Su
Journal:  Expert Rev Anti Infect Ther       Date:  2009-10       Impact factor: 5.091
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