Literature DB >> 15274480

Effect of Aloe vera (L.) Burm. fil. leaf gel and pulp extracts on kidney in type-II diabetic rat models.

Sehnaz Bolkent1, Nuriye Akev, Nurten Ozsoy, Meliha Sengezer-Inceli, Ayse Can, Okyar Alper, Refiye Yanardag.   

Abstract

Significant degenerative changes were observed in the kidney tissue of untreated neonatal streptozotocin (n0STZ)-induced type-II diabetic rats. These degenerative changes were diminished in the kidney tissue of diabetic animals given glibenclamide and Aloe leaf gel and pulp extracts. Kidney lipid peroxidation levels were increased in diabetic rats compared to healthy rats; these levels were higher in rats treated with glibenclamide than in those which received Aloe extracts. Serum urea and creatinine levels were higher in diabetic rats in comparison to healthy rats. The administration of Aloe gel extract and glibenclamide decreased serum urea and creatinine levels in comparison to diabetic controls. Only A. vera leaf gel extract showed improvement both in histological and biochemical parameters suggesting a protective effect of A. vera on mild damage caused by type-II diabetes on kidney tissue.

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Year:  2004        PMID： 15274480

Source DB:  PubMed          Journal:  Indian J Exp Biol        ISSN： 0019-5189            Impact factor:   0.818


  9 in total

1.  Possible hypoglycemic effect of Aloe vera L. high molecular weight fractions on type 2 diabetic patients.

Authors:  Akira Yagi; Sahar Hegazy; Amal Kabbash; Engy Abd-El Wahab
Journal:  Saudi Pharm J       Date:  2009-08-07       Impact factor: 4.330

2.  Plasma, tissue and urinary levels of aloin in rats after the administration of pure aloin.

Authors:  Mi-Young Park; Hoon-Jeong Kwon; Mi-Kyung Sung
Journal:  Nutr Res Pract       Date:  2008-03-31       Impact factor: 1.926

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Authors:  Mesfin Yimam; Lidia Brownell; Qi Jia
Journal:  World J Diabetes       Date:  2015-08-10

4.  Medicinal Plants with Multiple Effects on Diabetes Mellitus and Its Complications: a Systematic Review.

Authors:  Zeinab Nazarian-Samani; Robert D E Sewell; Zahra Lorigooini; Mahmoud Rafieian-Kopaei
Journal:  Curr Diab Rep       Date:  2018-08-13       Impact factor: 4.810

5.  Safety and Efficacy of Medicinal Plants Used to Manufacture Herbal Products with Regulatory Approval in Uganda: A Cross-Sectional Study.

Authors:  Bruhan Kaggwa; Henry Kyeyune; Edson Ireeta Munanura; Godwin Anywar; Stephen Lutoti; Jacqueline Aber; Lynn K Bagoloire; Anke Weisheit; Casim Umba Tolo; Pakoyo Fadhiru Kamba; Patrick Engeu Ogwang
Journal:  Evid Based Complement Alternat Med       Date:  2022-04-13       Impact factor: 2.650

6.  Effects of Aloe vera leaf gel extract on rat peritonitis model.

Authors:  Ayca Altincik; Ferah Sönmez; Cigdem Yenisey; Soner Duman; Ayse Can; Nuriye Akev; Sevin Kirdar; Murat Sezak
Journal:  Indian J Pharmacol       Date:  2014 May-Jun       Impact factor: 1.200

Review 7.  Aloe vera and Streptozotocin-Induced Diabetes Mellitus.

Authors:  Fatemeh Haghani; Mohammad-Reza Arabnezhad; Salman Mohammadi; Ali Ghaffarian-Bahraman
Journal:  Rev Bras Farmacogn       Date:  2022-03-10       Impact factor: 2.464

Review 8.  Phytochemical Classification of Medicinal Plants Used in the Treatment of Kidney Disease Based on Traditional Persian Medicine.

Authors:  Fatemeh Rabizadeh; Maryam Sadat Mirian; Rahele Doosti; Roya Kiani-Anbouhi; Elahe Eftekhari
Journal:  Evid Based Complement Alternat Med       Date:  2022-07-31       Impact factor: 2.650

9.  Blood glucose lowering activity of aloe based composition, UP780, in alloxan induced insulin dependent mouse diabetes model.

Authors:  Mesfin Yimam; Jifu Zhao; Brandon Corneliusen; Mandee Pantier; Lidia Brownell; Qi Jia
Journal:  Diabetol Metab Syndr       Date:  2014-05-24       Impact factor: 3.320
  9 in total

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