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Literature DB >> 15272499

The state of GPCR research in 2004.

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Year: 2004 PMID： 15272499 DOI： 10.1038/nrd1458

Source DB: PubMed Journal: Nat Rev Drug Discov ISSN： 1474-1776 Impact factor: 84.694

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19 in total

Review 1. Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain.

Authors: Bernard P Roques; Marie-Claude Fournié-Zaluski; Michel Wurm
Journal: Nat Rev Drug Discov Date: 2012-04 Impact factor: 84.694

2. A generic approach for the purification of signaling complexes that specifically interact with the carboxyl-terminal domain of G protein-coupled receptors.

Authors: Pascal Maurice; Avais M Daulat; Cédric Broussard; Julien Mozo; Guilhem Clary; Françoise Hotellier; Philippe Chafey; Jean-Luc Guillaume; Gilles Ferry; Jean A Boutin; Philippe Delagrange; Luc Camoin; Ralf Jockers
Journal: Mol Cell Proteomics Date: 2008-04-29 Impact factor: 5.911

Review 3. Membrane organization and dynamics of the G-protein-coupled serotonin1A receptor monitored using fluorescence-based approaches.

Authors: Thomas J Pucadyil; Shanti Kalipatnapu; Amitabha Chattopadhyay
Journal: J Fluoresc Date: 2005-09 Impact factor: 2.217

The state of GPCR research in 2004.

Review 1. Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain.

2. A generic approach for the purification of signaling complexes that specifically interact with the carboxyl-terminal domain of G protein-coupled receptors.

Review 3. Membrane organization and dynamics of the G-protein-coupled serotonin1A receptor monitored using fluorescence-based approaches.

Review 4. Minireview: More than just a hammer: ligand "bias" and pharmaceutical discovery.

Review 5. Translating in vitro ligand bias into in vivo efficacy.

Review 6. Membrane organization and function of the serotonin(1A) receptor.

Review 7. Design of cyclized selective melanotropins.

Review 8. The function of G-protein coupled receptors and membrane cholesterol: specific or general interaction?

9. Miniaturized GPCR signaling studies in 1536-well format.

10. Modulation of alpha2-adrenoceptor functions by heterotrimeric Galphai protein isoforms.